More information

Profile

Hanneke Takkenberg isProfessor of Management Education focusing on Women in Business at Rotterdam School of Management. She is co-executive director of the Erasmus Centre for Women and Organisations (ECWO) at RSM where she leads the centre’s research initiatives. Prof. Takkenberg brings decades of research excellence to this new professorship. Since 2012, she has been Professor of Clinical Decision Making in Cardio-Thoracic Interventions at Erasmus University Medical Center (MC) and she continues in this position three days a week. At the Erasmus MC, her current research focuses on prognosis and clinical and shared decision making in cardiovascular interventions, with special attention to male-female differences. Prof. Takkenberg’s own research at RSM broadly focuses on network analysis, with a particular focus on women’s organisations as well as personal networks. A key part of her current work is as part of the European Commission-funded Horizon2020 EQUAL4EUROPE research project that aims to develop and implement Gender Equality Plans in European Universities. She also facilitates within RSM’s Executive Education's women in business programmes, ECWO’s Open Masterclasses and RSM’s MBA, with a focus on gender balanced leadership. Hanneke’s work is broadly focused on empowering and connecting women to drive their individual careers forward, as well as achieving gender equality globally through advocacy and world leading research. At Erasmus MC, Prof. Takkenberg has worked to improve healthcare for women for patients and working conditions for female medical doctors. For that she was recognised with the 2018 Els Borst award for her scientific and societal efforts. In 2019, she received the Caty Asscher award for her efforts to achieve gender diversity in the Erasmus MC and Erasmus University Rotterdam. This was through the founding of VENA (2006), the Erasmus MC network for women in academia, her work as Chief Diversity Officer for EUR (2015-2018) and her initiation of the Diversity and Inclusion programme for the Erasmus MC in 2018. Prof. Takkenberg is currently chair of the Dutch Network for Women Professors (LNVH) board - a network of over 1300 women professors and associate professors, and is also Chief Diversity Officer at the Erasmus University MC. She obtained her MD at the Vrije University Amsterdam, her MSc Clinical Epidemiology at NIHES, and her PhD at Erasmus University Rotterdam (2002). She worked as a research fellow at Cedars-Sinai Medical Center, Los Angeles (1994-1996) and subsequently as a research clinician, assistant professor, and associate professor at the Department of Cardio-Thoracic Surgery of Erasmus University Medical Center prior to being appointed Professor in 2012.

Courses https_www.rsm.nl_ecwo_programmes

Publications

Academic (289)
  • Veen, K. M., Koudstaal, T., Hendriks, P. M., Takkenberg, J. JM., Boomars, K. A., & van den Bosch, A. E. (2024). Prognostic value of tricuspid valve regurgitation in patients with pulmonary arterial hypertension and CTEPH: A longitudinal study. IJC Heart and Vasculature, 51, Article 101342. https://doi.org/10.1016/j.ijcha.2024.101342

  • Notenboom, M. L., Melina, G., Veen, K. M., De Robertis, F., Coppola, G., De Siena, P., Navarra, E. M., Gaer, J., Ibrahim, M. E. K., El-Hamamsy, I., Takkenberg, J. J. M., & Yacoub, M. H. (2024). Long-Term Clinical and Echocardiographic Outcomes Following the Ross Procedure: A Post Hoc Analysis of a Randomized Clinical Trial. JAMA Cardiology, 9(1), 6-14. https://doi.org/10.1001/jamacardio.2023.4090

  • Meccanici, F., Thijssen, C. G. E., Heijmen, R. H., Geuzebroek, G. S. C., Ter Woorst, J. F., Gökalp, A. L., de Bruin, J. L., Gratama, D. N., Bekkers, J. A., van Kimmenade, R. R. J., Poyck, P., Peels, K., Post, M. C., Mokhles, M. M., Takkenberg, J. J. M., Roos-Hesselink, J. W., & Verhagen, H. J. M. (2024). Male-Female Differences in Acute Type B Aortic Dissection. Journal of the American Heart Association, 13(1), Article e029258. https://doi.org/10.1161/JAHA.122.029258

  • Meccanici, F., Bom, A. W., Knol, W. G., Gökalp, A. L., Thijssen, C. G. E., Bekkers, J. A., Geuzebroek, G. S. C., Mokhles, M. M., van Kimmenade, R. R. J., Budde, R. P. J., Takkenberg, J. J. M., & Roos-Hesselink, J. W. (2023). Male-female differences in thoracic aortic diameters at presentation of acute type A aortic dissection. IJC Heart and Vasculature, 49, Article 101290. https://doi.org/10.1016/j.ijcha.2023.101290

  • Veen, K., Joseph, A., Sossi, F., Jaber, P. B., Lansac, E., Das-Gupta, E., Aktaa, S., & Takkenberg, J. (2023). Standardized approach to extract candidate outcomes from literature for a standard outcome set: a case- and simulation study. BMC Medical Research Methodology, 23(1), Article 261. https://doi.org/10.1186/s12874-023-02052-x

  • Notenboom, M. L., Schuermans, A., Etnel, J. R. G., Veen, K. M., van de Woestijne, P. C., Rega, F. R., Helbing, W. A., Bogers, A. J. J. C., & Takkenberg, J. J. M. (2023). Paediatric aortic valve replacement: a meta-analysis and microsimulation study. European Heart Journal, 44(34), 3231-3246. https://doi.org/10.1093/eurheartj/ehad370

  • Notenboom, M. L., Rhellab, R., Etnel, J. R. G., van den Bogerd, N., Veen, K. M., Taverne, Y. J. H. J., Helbing, W. A., van de Woestijne, P. C., Bogers, A. J. J. C., & Takkenberg, J. J. M. (2023). Aortic valve repair in neonates, infants and children: a systematic review, meta-analysis and microsimulation study. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 64(3), Article ezad284. https://doi.org/10.1093/ejcts/ezad284

  • Meccanici, F., Thijssen, C. G. E., Gökalp, A. L., Bom, A. W., de Bruin, J. L., Bekkers, J. A., van Kimmenade, R. R. J., Geuzebroek, G. S. C., Poyck, P., Woorst, J. J. T., Peels, K., Sjatskig, J., Heijmen, R. H., Post, M. C., Mokhles, M. M., Verhagen, H. J. M., Takkenberg, J. J. M., & Roos-Hesselink, J. W. (2023). Long Term Health Related Quality of Life After Acute Type B Aortic Dissection: a Cross Sectional Survey Study. European Journal of Vascular and Endovascular Surgery, 66(3), 332-341. https://doi.org/10.1016/j.ejvs.2023.05.037

  • Meccanici, F., Thijssen, C. G. E., Dekker, S., Bons, L. R., Gökalp, A. L., De Rijke, Y. B., Takkenberg, J. J. M., Mokhles, M. M., Bekkers, J. A., Boersma, E., Bouwens, E., Van Der Bosch, A. E., Van Kimmenade, R. R. L., & Roos-Hesselink, J. W. (2023). Circulating biomarkers associated with aortic diameter in male and female patients with thoracic aortic disease: A cross-sectional study. Open Heart, 10(1), Article 002317. https://doi.org/10.1136/openhrt-2023-002317

  • Grashuis, P., Khargi, S. D. M., Veen, K., el Osrouti, A., Bemelmans-Lalezari, S., Cornette, J. M. J., Roos-Hesselink, J. W., Takkenberg, J. J. M., & Mokhles, M. M. (2023). Pregnancy outcomes in women with a mitral valve prosthesis: A systematic review and meta-analysis. JTCVS Open, 14, 102-122. https://doi.org/10.1016/j.xjon.2023.05.001

  • Voigt, K. R., Gökalp, A. L., Papageorgiou, G., Bogers, A. J. J. C., Takkenberg, J. J. M., Mokhles, M. M., & Bekkers, J. A. (2023). Male-Female Differences in Ascending Aortic Aneurysm Surgery: 25-Year Single Center Results. Seminars in Thoracic and Cardiovascular Surgery, 35(2), 300-308. https://doi.org/10.1053/j.semtcvs.2022.01.002

  • Veen, K. M., Papageorgiou, G., Zijderhand, C. F., Mokhles, M. M., Brugts, J. J., Manintveld, O. C., Constantinescu, A. A., Bekkers, J. A., Takkenberg, J. J. M., Bogers, A. J. J. C., & Caliskan, K. (2023). The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant. Frontiers of Medicine, 17(3), 527-533. https://doi.org/10.1007/s11684-022-0967-5

  • Stoica, S., Beard, C., Takkenberg, J. J. M., Mokhles, M. M., Turner, M., Pepper, J., Hopewell-Kelly, N., Benedetto, U., Nashef, S. A. M., El-Hamamsy, I., Skillington, P., Glauber, M., De Paulis, R., Tseng, E., Meuris, B., Sitges, M., Delgado, V., Krane, M., Kostolny, M., & Pufulete, M. (2023). Formal consensus study on surgery to replace the aortic valve in adults aged 18-60 years. Heart, 109(11), 857-865. https://doi.org/10.1136/heartjnl-2022-321740

  • Thijssen, C. G. E., Dekker, S., Bons, L. R., Geenen, L. W., Gökalp, A. L., Takkenberg, J. J. M., Mokhles, M. M., Bekkers, J. A., Boersma, E., Bouwens, E., van Kimmenade, R. R. J., & Roos-Hesselink, J. W. (2023). Novel biomarkers associated with thoracic aortic disease. International Journal of Cardiology, 378, 115-122. https://doi.org/10.1016/j.ijcard.2023.02.006

  • Memis, F., Thijssen, C. G. E., Gökalp, A. L., Notenboom, M. L., Meccanici, F., Mokhles, M. M., van Kimmenade, R. R. J., Veen, K. M., Geuzebroek, G. S. C., Sjatskig, J., ter Woorst, F. J., Bekkers, J. A., Takkenberg, J. J. M., & Roos-Hesselink, J. W. (2023). Elective Ascending Aortic Aneurysm Surgery in the Elderly. Journal of Clinical Medicine, 12(5), Article 2015. https://doi.org/10.3390/jcm12052015

  • Gökalp, A. L., Thijssen, C. G. E., Bekkers, J. A., Roos-Hesselink, J. W., Bogers, A. J. J. C., Geuzebroek, G. S. C., Houterman, S., Takkenberg, J. J. M., & Mokhles, M. M. (2023). Male-female differences in contemporary elective ascending aortic surgery: insights from the Netherlands Heart Registration. Annals of Cardiothoracic Surgery, 12(6), 577-587. https://doi.org/10.21037/acs-2022-adw-fs-0139

  • Thijssen, C. G. E., Mutluer, F. O., Van Der Toorn, J. E., Bons, L. R., Gökalp, A. L., Takkenberg, J. J. M., Mokhles, M. M., Van Kimmenade, R. R. J., Vernooij, M. W., Van Der Lugt, A., Budde, R. P. J., Roos-Hesselink, J. W., Kavousi, M., & Bos, D. (2022). Longitudinal changes of thoracic aortic diameters in the general population aged 55 years or older. Heart, 108(22), 1767-1776. https://doi.org/10.1136/heartjnl-2021-320574

  • Wang, X., Andrinopoulou, E. R., Veen, K. M., Bogers, A. J. J. C., & Takkenberg, J. J. M. (2022). Statistical primer: an introduction to the application of linear mixed-effects models in cardiothoracic surgery outcomes research-a case study using homograft pulmonary valve replacement data. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 62(4), Article ezac429. https://doi.org/10.1093/ejcts/ezac429

  • Abjigitova, D., Veen, K. M., van Tussenbroek, G., Mokhles, M. M., Bekkers, J. A., Takkenberg, J. J. M., & Bogers, A. J. J. C. (2022). Cerebral protection in aortic arch surgery: systematic review and meta-analysis. Interactive Cardiovascular and Thoracic Surgery, 35(3), Article ivac128. https://doi.org/10.1093/icvts/ivac128

  • Veen, K., Wang, X., Soliman, O., de By, T. M., Mokhles, M. M., Caliskan, K., & Takkenberg, J. J. (2022). Novel Machine Learning Algorithms for Predicting Early Right Heart Failure Post Left Ventricular Assist Device Implantation. Journal of Heart and Lung Transplantation, 41(4, Supplement), S25. https://doi.org/10.1016/j.healun.2022.01.054

  • Van Hoof, L., Rega, F., Golesworthy, T., Verbrugghe, P., Austin, C., Takkenberg, J. J. M., Pepper, J. R., & Treasure, T. (2021). Personalised external aortic root support for elective treatment of aortic root dilation in 200 patients. Heart, 107(22), 1790-1795. https://doi.org/10.1136/heartjnl-2021-319300

  • Romeo, J. L. R., Papageorgiou, G., Da Costa, F. F. D., Sievers, H. H., Bogers, A. J. J. C., El-Hamamsy, I., Skillington, P. D., Wynne, R., Mastrobuoni, S., El Khoury, G., Takkenberg, J. J. M., & Mokhles, M. M. (2021). Long-term Clinical and Echocardiographic Outcomes in Young and Middle-aged Adults Undergoing the Ross Procedure. JAMA Cardiology, 6(5), 539-548. https://doi.org/10.1001/jamacardio.2020.7434

  • Gravesteijn, B., Krijkamp, E., Value Based Operation Room Triage team collaborators, Busschbach, J., Geleijnse, G., Helmrich, I. R., Bruinsma, S., van Lint, C., van Veen, E., Steyerberg, E., Verhoef, C., van Saase, J., Lingsma, H., & Baatenburg de Jong, R. (2021). Minimizing Population Health Loss in Times of Scarce Surgical Capacity During the Coronavirus Disease 2019 Crisis and Beyond: A Modeling Study. Value in Health, 24(5), 648-657. https://doi.org/10.1016/j.jval.2020.12.010

  • Sadeghi, H., Wahadat, A. R., Dereci, A., Budde, R. P. J., Tanis, W., Roos-Hesselink, J. W., Takkenberg, H., Taverne, Y. J. H. J., Mahtab, E. A. F., & Bogers, A. J. J. C. (2021). Remote multidisciplinary heart team meetings in immersive virtual reality: A first experience during the COVID-19 pandemic. BMJ Innovations, 7(2), 311-315. https://doi.org/10.1136/bmjinnov-2021-000662

  • Etnel, J. R. G., Bons, L. R., De Heer, F., Robbers-Visser, D., Van Beynum, I. M., Straver, B., Jongbloed, M. R. M., Kiès, P., Slieker, M. G., Van Dijk, A. P. J., Kluin, J., Bertels, R. A., Utens, E. M. W. J., The, R., Van Galen, E., Mulder, B. J. M., Blom, N. A., Hazekamp, M. G., Roos-Hesselink, J. W., ... Takkenberg, J. J. M. (2021). Patient information portal for congenital aortic and pulmonary valve disease: A stepped-wedge cluster randomised trial. Open Heart, 8(1), Article e001252. https://doi.org/10.1136/openhrt-2020-001252

  • Takkenberg, H. (2021). Observed Versus Expected Survival After HTX: Is the Cup Half Full or Half Empty? Annals of Thoracic Surgery, 111(3), 898. https://doi.org/10.1016/j.athoracsur.2020.06.094

  • Veen, K., Mokhles, M., Soliman, O., de By, TMMH., Mohacsi, P., Schoenrath, F., Paluszkiewicz, L., Netuka, I., Bogers, A., Takkenberg, H., & Caliskan, K. (2021). Clinical impact and 'natural' course of uncorrected tricuspid regurgitation after implantation of a left ventricular assist device: an analysis of the European Registry for Patients with Mechanical Circulatory Support (EUROMACS). European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 59(1), 207-216. https://doi.org/10.1093/ejcts/ezaa294

  • Noruzi, A., Takkenberg, H., Kayapa, B., Verhemel, A., & Gadjradj, PS. (2021). Honorary authorship in cardiothoracic surgery. Journal of Thoracic and Cardiovascular Surgery, 161(1), 156-162.e1. https://doi.org/10.1016/j.jtcvs.2019.10.104

  • Melina, G., De Robertis, F., Gaer, JA., Angeloni, E., El-Hamamsy, I., Bahrami, T., Pepper, JR., Takkenberg, H., & Yacoub, MH. (2021). Long-term survival after xenograft versus homograft aortic root replacement: Results from a prospective randomized trial. Journal of Thoracic and Cardiovascular Surgery, 161(1), 57-65. https://doi.org/10.1016/j.jtcvs.2019.09.119

  • Veen, K. M., Hart, E. A., Mokhles, M. M., de Jong, P. L., de Heer, F., van Boven, W.-J. P., van den Heuvel, T., Siregar, S., Braun, J., Chamuleau, S. A. J., Meijer, R., de Herder, W. W., Takkenberg, J. J. M., & Bogers, A. J. J. C. (2020). Outcomes after Tricuspid Valve Replacement for Carcinoid Heart Disease: A Multicenter Study*. Structural Heart, 4(2), 122-130. https://doi.org/10.1080/24748706.2019.1706795

  • Gökalp, A., Thijssen, C., Hesselink, J., & Takkenberg, H. (2020). Dissecting sex and gender. Journal of Thoracic and Cardiovascular Surgery, 160(2), E11-E11. https://doi.org/10.1016/j.jtcvs.2020.03.148

  • Romeo, J., Papageorgiou, G., Takkenberg, H., Hesselink, J., Leeuwen, W., Cornette, JMJ., Rizopoulos, D., Bogers, A., & Mokhles, M. (2020). Influence of pregnancy on long-term durability of allografts in right ventricular outflow tract. Journal of Thoracic and Cardiovascular Surgery, 159, 1508-1516.e1. https://doi.org/10.1016/j.jtcvs.2019.08.083

  • Takkenberg, H. (2020). Durability of Mitral Valve Bioprostheses: A Meta-Analysis of Long-Term Follow-up Studies. Annals of Thoracic Surgery, 109(2), 611-611. https://doi.org/10.1016/j.athoracsur.2019.08.053

  • Romeo, J., Etnel, J., Takkenberg, H., Hesselink, J., Helbing, WA., Woestijne, P., Bogers, A., & Mokhles, M. (2020). Outcome after surgical repair of tetralogy of Fallot: A systematic review and meta-analysis. Journal of Thoracic and Cardiovascular Surgery, 159(1), 220-+. https://doi.org/10.1016/j.jtcvs.2019.08.127

  • Angst, I., Weernink, MGM., Kil, PJ., van Til, JA., Cornel, EB., & Takkenberg, H. (2020). Development and usability testing of a multi-criteria value clarification methods for patients with localized prostate cancer. Health Informatics Journal, 26(1), 486-498. https://doi.org/10.1177/1460458219832055

  • Chang, CC., Veen, K., Hahn, RT., Bogers, A., Latib, A., Oei, F., Abdelghani, M., Modolo, R., Ho, SYW., Abdel-Wahab, M., Fattouch, K., Bosmans, J., Caliskan, K., Taramasso, M., Serruys, PWJC., Bax, JJJ., Mieghem, N., Takkenberg, H., Lurz, P., ... Soliman, O. (2020). Uncertainties and challenges in surgical and transcatheter tricuspid valve therapy: a state-of-the-art expert review. European Heart Journal, 41(20), 1932-1940. https://doi.org/10.1093/eurheartj/ehz614

  • Huygens, S., Ramos, IC., Bouten, CVC., Kluin, J., Chiu, ST., Grunkemeier, GL., Takkenberg, H., & Molken, M. (2020). Early cost-utility analysis of tissue-engineered heart valves compared to bioprostheses in the aortic position in elderly patients. The European Journal Of Health Economics, 21(4), 557-572. https://doi.org/10.1007/s10198-020-01159-y

  • Thijssen, C., Dekker, S., Bons, L., Gökalp, A., Kauling, M., Bosch, A., Cuypers, J., Utens, L., Kimmenade, R., Takkenberg, H., Roos, LMH., Goossens, E., & Hesselink, J. (2020). Health-related quality of life and lived experiences in males and females with thoracic aortic disease and their partners. Open Heart, 7(2), Article e001419. https://doi.org/10.1136/openhrt-2020-001419

  • Veen, K., Quanjel, T., Mokhles, M., Bogers, A., & Takkenberg, H. (2020). Tricuspid valve replacement: an appraisal of 45 years of experience. Interactive Cardiovascular and Thoracic Surgery, 30(6), 896-903. https://doi.org/10.1093/icvts/ivaa033

  • Zijderhand, C., Veen, K., Caliskan, K., Schoonen, T., Mokhles, M., Bekkers, J., Manintveld, O., Constantinescu, A., Brugts, J., Bogers, A., & Takkenberg, H. (2020). Biatrial Versus Bicaval Orthotopic Heart Transplantation: A Systematic Review and Meta-Analysis. Annals of Thoracic Surgery, 110(2), 684-691. https://doi.org/10.1016/j.athoracsur.2019.12.048

  • Romeo, J., Takkenberg, H., Cuypers, J., Groot, N., Woestijne, P., Bruining, N., Bogers, A., & Mokhles, M. (2020). Timing of pulmonary valve replacement in patients with corrected Fallot to prevent QRS prolongation. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 58(3), 559-566. https://doi.org/10.1093/ejcts/ezaa049

  • Thijssen, C., Doze, DE., Gökalp, A., Timmermans, J., Peters, JB., Elbers-van de Ven, LHC., van Royen, N., Takkenberg, H., Hesselink, J., & Kimmenade, R. (2020). Male–female differences in quality of life and coping style in patients with Marfan syndrome and hereditary thoracic aortic diseases. Journal of Genetic Counseling, 29(6), 1259-1269. https://doi.org/10.1002/jgc4.1288

  • Veen, K., de Angst, IB., Mokhles, M., Westgeest, HM., Kuppen, M., Groot, C., Gerritsen, WR., Kil, PJM., & Takkenberg, H. (2020). A clinician’s guide for developing a prediction model: a case study using real?world data of patients with castration?resistant prostate cancer. Journal of Cancer Research and Clinical Oncology, 146, 2067-2075. https://doi.org/10.1007/s00432-020-03286-8

  • Etnel, J., Groot, J., Jabri, M., Mesch, A., Nobel, N., Bogers, A., & Takkenberg, H. (2020). Do risk visualizations improve the understanding of numerical risks? A randomized, investigator-blinded general population survey. International Journal of Medical Informatics, 135, Article 104005. https://doi.org/10.1016/j.ijmedinf.2019.104005

  • Bons, L., Sedghi Gamechi, Z., Thijssen, C., Kofoed, KF., Pedersen, JH., Saghir, Z., Takkenberg, H., Kardys, I., Budde, R., Bruijne, M., & Hesselink, J. (2020). Growth of the thoracic aorta in the smoking population: The Danish Lung Cancer Screening Trial. International Journal of Cardiology, 299, 276-281. https://doi.org/10.1016/j.ijcard.2019.06.010

  • Veen, K., Etnel, J., Quanjel, T., Mokhles, M., Huygens, S., Rasheed, M., Oei, F., Cate, F., Bogers, A., & Takkenberg, H. (2020). Outcomes after surgery for functional tricuspid regurgitation: a systematic review and meta-analysis. European heart journal. Quality of care & clinical outcomes, 6, 10-18. https://doi.org/10.1093/ehjqcco/qcz032

  • Etnel, J., Huygens, S., Grashuis, P., Pekbay, B., Papageorgiou, G., Hesselink, J., Bogers, A., & Takkenberg, H. (2019). Bioprosthetic Aortic Valve Replacement in Nonelderly Adults A Systematic Review, Meta-Analysis, and Microsimulation. Circulation-cardiovascular Quality And Outcomes, 12(2), Article e005481. https://doi.org/10.1161/circoutcomes.118.005481

  • Veen, K., Mokhles, M., Braun, J., Versteegh, MIM., Bogers, A., & Takkenberg, H. (2019). Male-female differences in characteristics and early outcomes of patients undergoing tricuspid valve surgery: a national cohort study in the Netherlands. European Journal of Cardio-thoracic Surgery, 55(5), 859-866. https://doi.org/10.1093/ejcts/ezy390

  • Angst, I., Kil, PJM., Bangma, CH., & Takkenberg, H. (2019). Should we involve patients more actively? Perspectives of the multidisciplinary team on shared decision-making for older patients with metastatic castration-resistant prostate cancer. Journal of Geriatric Oncology, 10(4), 653-658. https://doi.org/10.1016/j.jgo.2018.12.003

  • Huygens, S., Etnel, J., Hanif, M., Bekkers, J., Bogers, A., Molken, M., & Takkenberg, H. (2019). Bioprosthetic aortic valve replacement in elderly patients: Meta-analysis and microsimulation. Journal of Thoracic and Cardiovascular Surgery, 157(6), 2189-+. https://doi.org/10.1016/j.jtcvs.2018.10.040

  • Huygens, S., Molken, M., Noruzi, A., Etnel, J., Corro Ramos, I., Bouten, CVC., Kluin, J., & Takkenberg, H. (2019). What Is the Potential of Tissue-Engineered Pulmonary Valves in Children? Annals of Thoracic Surgery, 107(6), 1845-1853. https://doi.org/10.1016/j.athoracsur.2018.11.066

  • Siregar, S., Nieboer, D., Versteegh, MIM., Steyerberg, E., & Takkenberg, H. (2019). Methods for updating a risk prediction model for cardiac surgery: a statistical primer. Interactive CardioVascular and Thoriac Surgery, 28(3), 333-338. https://doi.org/10.1093/icvts/ivy338

  • Thijssen, C., Bons, L., Gökalp, A., Van Kimmenade, RRJ., Mokhles, M., Pelliccia, A., Takkenberg, H., & Hesselink, J. (2019). Exercise and sports participation in patients with thoracic aortic disease: a review. Expert Review of Cardiovascular Therapy, 17(4), 251-266. https://doi.org/10.1080/14779072.2019.1585807

  • de Heer, F., Gokalp, AL., Kluin, J., & Takkenberg, H. (2019). Measuring what matters to the patient: health related quality of life after aortic valve and thoracic aortic surgery. General Thoracic and Cardiovascular Surgery, 67(1), 37-43. https://doi.org/10.1007/s11748-017-0830-9

  • Huygens, S., van der Kley, F., Bekkers, J., Bogers, A., Takkenberg, H., & Molken, M. (2019). Beyond the clinical impact of aortic and pulmonary valve implantation: health-related quality of life, informal care and productivity. European Journal of Cardio-thoracic Surgery, 55(4), 751-759. https://doi.org/10.1093/ejcts/ezy382

  • Veen, K., Mokhles, M., Hesselink, J., Rebel, B., Takkenberg, H., & Bogers, A. (2019). Reconstructive surgery for Ebstein anomaly: three decades of experience. European Journal of Cardio-thoracic Surgery, 56(2), 385-392. https://doi.org/10.1093/ejcts/ezz022

  • de Heer, F., Kluin, J., Elkhoury, G., Jondeau, G., Enriquez-Sarano, M., Schafers, HJ., Takkenberg, H., Kelley, S., & Leavitt, K. (2019). AVIATOR: An open international registry to evaluate medical and surgical outcomes of aortic valve insufficiency and ascending aorta aneurysm. Journal of Thoracic and Cardiovascular Surgery, 157(6), 2202-+. https://doi.org/10.1016/j.jtcvs.2018.10.076

  • Lansac, E., Youssefi, P., de Heer, F., Bavaria, J., de Kerchove, L., El-Hamamsy, I., Elkhoury, G., Enriquez-Sarano, M., Jondeau, LG., Kluin, J., Pibarot, P., Schäfers, HJ., Vanoverschelde, JL., & Takkenberg, H. (2019). Aortic Valve Surgery in Nonelderly Patients: Insights Gained From AVIATOR. Seminars in Thoracic and Cardiovascular Surgery, 31(4), 643-649. https://doi.org/10.1053/j.semtcvs.2019.05.033

  • Takkenberg, H. (2019). Invited Commentary. Annals of Thoracic Surgery, 108(2), 551. https://doi.org/10.1016/j.athoracsur.2019.05.012

  • Hickey, GL., Kontopantelis, E., Takkenberg, H., & Beyersdorf, F. (2019). Statistical Primer: Checking Model Assumptions With Regression Diagnostics. Interactive Cardiovascular and Thoracic Surgery, 28(1), 1-8. https://doi.org/10.1093/icvts/ivy207

  • Gökalp, A., de Heer, F., Etnel, J., Kluin, J., & Takkenberg, H. (2019). Clinical and Quality of Life Outcomes After Aortic Valve Replacement and Aortic Root Surgery in Adult Patients <65 Years Old. Annals of Cardiothoracic Surgery, 8(3), 372-382. https://doi.org/10.21037/acs.2019.04.07

  • Papageorgiou, G., Mokhles, M., Takkenberg, H., & Rizopoulos, D. (2019). Individualized Dynamic Prediction of Survival With the Presence of Intermediate Events. Statistics in Medicine, 38(30), 5623-5640. https://doi.org/10.1002/sim.8387

  • Gökalp, A., & Takkenberg, H. (2019). Decision-Making in Thoracic Aortic Aneurysm Surgery-Clinician and Patient View. Seminars in Thoracic and Cardiovascular Surgery, 31(4), 638-642. https://doi.org/10.1053/j.semtcvs.2019.05.032

  • de Heer, F., Lansac, E., El-Hamamsy, I., Pibarot, P., de Kerchove, L., El Khoury, G., Schafers, HJ., Takkenberg, H., & Kluin, J. (2019). The AVIATOR registry: the importance of evaluating long-term patient outcomes. Annals of Cardiothoracic Surgery, 8(3), 393-395. https://doi.org/10.21037/acs.2019.04.08

  • Romeo, J., Mokhles, M., Woestijne, P., Bosch, A., Beynum, I., Takkenberg, H., & Bogers, A. (2019). Long-term clinical outcome and echocardiographic function of homografts in the right ventricular outflow tract. European Journal of Cardio-thoracic Surgery, 55, 518-526.

  • Veen, K., Caliskan, K., de By, T., Mokhles, M., Soliman, O., Mohacsi, P., Schoenrath, F., Gummert, J., Paluszkiewicz, L., Netuka, I., Loforte, A., Pya, Y., Takkenberg, H., & Bogers, A. (2019). Outcomes after tricuspid valve surgery concomitant with left ventricular assist device implantation in the EUROMACS registry: a propensity score matched analysis. European Journal of Cardio-thoracic Surgery, 56(6), 1081-1089. https://doi.org/10.1093/ejcts/ezz208

  • Papageorgiou, G., Grant, SW., Takkenberg, H., & Mokhles, M. (2018). Statistical primer: how to deal with missing data in scientific research? Interactive CardioVascular and Thoriac Surgery, 27(2), 153-158. https://doi.org/10.1093/icvts/ivy102

  • Mokhles, S., Nuyttens, JJME., de Mol, M., Aerts, J., Maat, Birim, O., Bogers, A., & Takkenberg, H. (2018). Treatment selection of early stage non-small cell lung cancer: the role of the patient in clinical decision making. BMC Cancer, 18, Article 79. https://doi.org/10.1186/s12885-018-3986-5

  • Huygens, S., Takkenberg, H., & Molken, M. (2018). Systematic review of model-based economic evaluations of heart valve implantations. The European Journal Of Health Economics, 19(2), 241-255. https://doi.org/10.1007/s10198-017-0880-z

  • Huygens, S., Goossens, L., van Erkelens, JA., Takkenberg, H., & Molken, M. (2018). How much does a heart valve implantation cost and what are the health care costs afterwards? Open Heart, 5(1), Article UNSP e000672. https://doi.org/10.1136/openhrt-2017-000672

  • da Costa, FDA., Etnel, J., Charitos, EI., Sievers, HH., Stierle, U., Fornazari, D., Takkenberg, H., Bogers, AJJC., & Mokhles, M. (2018). Decellularized Versus Standard Pulmonary Allografts in the Ross Procedure: Propensity-Matched Analysis. Annals of Thoracic Surgery, 105(4), 1205-1213. https://doi.org/10.1016/j.athoracsur.2017.09.057

  • Treasure, T., King, A., Lemp, LH., Golesworthy, T., Pepper, J., & Takkenberg, H. (2018). Developing a shared decision support framework for aortic root surgery in Marfan syndrome. Heart, 104(6), 480-486. https://doi.org/10.1136/heartjnl-2017-311598

  • Valen, R., Gameren, M., Mokhles, M., Takkenberg, H., Horst, M., Hofland, J., & Bogers, A. (2018). Effectiveness of adherence to a preoperative antiplatelet and anticoagulation cessation protocol in cardiac surgery. Interactive CardioVascular and Thoriac Surgery, 26(5), 820-825. https://doi.org/10.1093/icvts/ivx401

  • Soloukey Tbalvandany, S., Maat, Cornelissen, R., Nuyttens, JJME., & Takkenberg, H. (2018). WWW mesothelioma information: Surfing on unreliable waters. A cross-sectional study into the content and quality of online informational resources for mesothelioma patients. Patient Education and Counseling, 101(6), 1088-1094. https://doi.org/10.1016/j.pec.2018.01.009

  • Romeo, J., Takkenberg, H., Hesselink, J., Hanif, M., Cornette, JMJ., Leeuwen, W., Dijk, A., Bogers, A., & Mokhles, M. (2018). Outcomes of Pregnancy After Right Ventricular Outflow Tract Reconstruction With an Allograft Conduit. Journal of the American College of Cardiology, 71(23), 2656-2665. https://doi.org/10.1016/j.jacc.2018.03.522

  • Treasure, T., & Takkenberg, H. (2018). Randomized trials and big data analysis: we need the best of both worlds. European Journal of Cardio-thoracic Surgery, 53(5), 910-914. https://doi.org/10.1093/ejcts/ezy056

  • Romeo, J., Papageorgiou, G., Woestijne, P., Takkenberg, H., Westenber, LEH., Beynum, I., Bogers, A., & Mokhles, M. (2018). Downsized cryopreserved and standard-sized allografts for right ventricular outflow tract reconstruction in children: long-term single-institutional experience. Interactive CardioVascular and Thoriac Surgery, 27(2), 257-263. https://doi.org/10.1093/icvts/ivy057

  • Andrinopoulou, E., Eilers, P., Takkenberg, H., & Rizopoulos, D. (2018). Improved dynamic predictions from joint models of longitudinal and survival data with time-varying effects using P-splines. Biometrics, 74(2), 685-693. https://doi.org/10.1111/biom.12814

  • Tomsic, A., Arabkhani, B., Schoones, JW., van Brakel, TJ., Takkenberg, H., Palmen, M., & Klautz, RJM. (2018). Outcome reporting for surgical treatment of degenerative mitral valve disease: a systematic review and critical appraisal. Interactive CardioVascular and Thoriac Surgery, 26(4), 566-572. https://doi.org/10.1093/icvts/ivx370

  • Etnel, J., Grashuis, P., Huygens, S., Pekbay, B., Papageorgiou, G., Helbing, WA., Hesselink, J., Bogers, A., Mokhles, M., & Takkenberg, H. (2018). The Ross Procedure: A Systematic Review, Meta-Analysis, and Microsimulation. Circulation-cardiovascular Quality And Outcomes, 11(12), Article e004748. https://doi.org/10.1161/circoutcomes.118.004748

  • Romeo, J., Papageorgiou, G., Takkenberg, H., & Mokhles, M. (2018). The right time-dependent statistics: this is the moment. European Journal of Cardio-thoracic Surgery, 54(6), 1145-1145. https://doi.org/10.1093/ejcts/ezy184

  • Veen, K., Muslem, R., Soliman, O., Caliskan, K., Kolff, MEA., Dousma, D., Manintveld, O., Birim, O., Bogers, A., & Takkenberg, H. (2018). Left ventricular assist device implantation with and without concomitant tricuspid valve surgery: a systematic review and meta-analysis. European Journal of Cardio-thoracic Surgery, 54(4), 644-651. https://doi.org/10.1093/ejcts/ezy150

  • Etnel, J., Helbing, WA., Hesselink, J., The, R., Bogers, A., & Takkenberg, H. (2018). Patient and physician view on patient information and decision-making in congenital aortic and pulmonary valve surgery. Open Heart, 5(2), Article e000872. https://doi.org/10.1136/openhrt-2018-000872

  • Mokhles, M., Soloukey Tbalvandany, S., Siregar, S., Versteegh, MIM., Noyez, L., van de Putte, B., Vonk, ABA., Hesselink, J., Bogers, A., & Takkenberg, H. (2018). Male-female differences in aortic valve and combined aortic valve/coronary surgery: a national cohort study in the Netherlands. Open Heart, 5(2), Article e000868. https://doi.org/10.1136/openhrt-2018-000868

  • Korteland, N., Takkenberg, H., Bogers, A., & Hesselink, J. (2017). A devilish dilemma. Interactive CardioVascular and Thoriac Surgery, 24(4), 641-642. https://doi.org/10.1093/icvts/ivw377

  • Korteland, N., Takkenberg, H., Bogers, A., & Hesselink, J. (2017). Treatment solution for a devilish dilemma by Korteland et al. Interactive CardioVascular and Thoriac Surgery, 24(4), 642-643. https://doi.org/10.1093/icvts/ivx097

  • Korteland, N., Ahmed, Y., Koolbergen, DR., Brouwer, M., de Heer, F., Kluin, J., Bruggemans, EF., Klautz, RJM., Stiggelbout, AM., Bucx, JJJ., Hesselink, J., Polak, P., Markou, T., Broek, I., Ligthart, R., Bogers, A., & Takkenberg, H. (2017). Does the Use of a Decision Aid Improve Decision Making in Prosthetic Heart Valve Selection? A Multicenter Randomized Trial. Circulation-cardiovascular Quality And Outcomes, 10(2), Article UNSP e003178. https://doi.org/10.1161/circoutcomes.116.003178

  • Mokhles, S., Takkenberg, H., & Treasure, T. (2017). Evidence-Based and Personalized Medicine. It's AND not OR. Annals of Thoracic Surgery, 103(1), 351-360. https://doi.org/10.1016/j.athoracsur.2016.08.100

  • Mookhoek, A., Krishnan, K., Chitsaz, S., Kuang, H. D., Ge, L., Schoof, PH., Bogers, A., Takkenberg, H., & Tseng, EE. (2017). Biomechanics of Failed Pulmonary Autografts Compared to Native Aortic Roots. Annals of Thoracic Surgery, 103(5), 1482-1488. https://doi.org/10.1016/j.athoracsur.2016.08.061

  • Etnel, J., van Dijk, APJ., Kluin, J., Bertels, RA., Utens, L., van Galen, E., The, R., Bogers, A., & Takkenberg, H. (2017). Development of an Online, Evidence-Based Patient Information Portal for Congenital Heart Disease: A Pilot Study. Frontiers in Cardiovascular Medicine, 4, Article Unsp 25. https://doi.org/10.3389/fcvm.2017.00025

  • Mokhles, S., Maat, Aerts, J., Nuyttens, JJME., Bogers, A., & Takkenberg, H. (2017). Opinions of lung cancer clinicians on shared decision making in early-stage non-small-cell lung cancer. Interactive CardioVascular and Thoriac Surgery, 25(2), 278-284. https://doi.org/10.1093/icvts/ivx103

  • Mokhles, S., Macbeth, F., Treasure, T., Younes, RN., Rintoul, RC., Fiorentino, F., Bogers, A., & Takkenberg, H. (2017). Systematic lymphadenectomy versus sampling of ipsilateral mediastinal lymph-nodes during lobectomy for non-small-cell lung cancer: a systematic review of randomized trials and a meta-analysis. European Journal of Cardio-thoracic Surgery, 51(6), 1149-1156. https://doi.org/10.1093/ejcts/ezw439

  • Andrinopoulou, E., Rizopoulos, D., Takkenberg, H., & Lesaffre, E. (2017). Combined dynamic predictions using joint models of two longitudinal outcomes and competing risk data. Statistical Methods in Medical Research, 26(4), 1787-1801. https://doi.org/10.1177/0962280215588340

  • Mokhles, S., Takkenberg, H., Treasure, T., & Macbeth, F. (2017). Systematic lymphadenectomy: 'meta-lysis' does not need meta-analysis. European Journal of Cardio-thoracic Surgery, 52(5), 1012-1013. https://doi.org/10.1093/ejcts/ezx300

  • Korteland, NM., Etnel, J., Arabkhani, B., Mokhles, M., Mohamad, A., Hesselink, J., Bogers, A., & Takkenberg, H. (2017). Mechanical aortic valve replacement in non-elderly adults: meta-analysis and microsimulation. European Heart Journal, 38(45), 3370-3377. https://doi.org/10.1093/eurheartj/ehx199

  • Oldenburger, NJ., Mank, A., Etnel, J., Takkenberg, H., & Helbing, WA. (2016). Drug therapy in the prevention of failure of the Fontan circulation: a systematic review. Cardiology in the Young, 26(5), 842-850. https://doi.org/10.1017/S1047951115002747

  • Kuhlmann, R., Etnel, J., Hesselink, J., Jeekel, J., Bogers, A., & Takkenberg, H. (2016). Systematic review and meta-analysis of music interventions in hypertension treatment: a quest for answers. BMC Cardiovascular Disorders, 16. https://doi.org/10.1186/s12872-016-0244-0

  • Baggen, V., Driessen, MMP., Post, MC., Vandijk, AP., Hesselink, J., Bosch, A., Takkenberg, H., & Sieswerda, GT. (2016). Echocardiographic findings associated with mortality or transplant in patients with pulmonary arterial hypertension: A systematic review and meta-analysis. Netherlands Heart Journal, 24(6), 374-389. https://doi.org/10.1007/s12471-016-0845-3

  • Etnel, J., Elmont, L., Ertekin, E., Mokhles, M., Heuvelman, H., Hesselink, J., de Jong, PL., Helbing, WA., Bogers, A., & Takkenberg, H. (2016). Outcome after aortic valve replacement in children: A systematic review and meta-analysis. Journal of Thoracic and Cardiovascular Surgery, 151(1), 143-+. https://doi.org/10.1016/j.jtcvs.2015.09.083

  • Mokhles, S., Macbeth, F., Farewell, V., Fiorentino, F., Williams, NR., Younes, RN., Takkenberg, H., & Treasure, T. (2016). Meta-analysis of colorectal cancer follow-up after potentially curative resection. British Journal of Surgery, 103(10), 1259-1268. https://doi.org/10.1002/bjs.10233

  • Rizopoulos, D., Taylor, JMG., Rosmalen, J., Steyerberg, E., & Takkenberg, H. (2016). Personalized screening intervals for biomarkers using joint models for longitudinal and survival data. Biostatistics, 17(1), 149-164. https://doi.org/10.1093/biostatistics/kxv031

  • Siregar, S., Nieboer, D., Vergouwe, Y., Versteegh, MIM., Noyez, L., Vonk, ABA., Steyerberg, E., & Takkenberg, H. (2016). Improved Prediction by Dynamic Modeling An Exploratory Study in the Adult Cardiac Surgery Database of the Netherlands Association for Cardio-Thoracic Surgery. Circulation-cardiovascular Quality And Outcomes, 9(2), 171-181. https://doi.org/10.1161/CIRCOUTCOMES.114.001645

  • Treasure, T., Takkenberg, H., & Pepper, J. (2016). Surgical management of aortic root disease in Marfan syndrome and other congenital disorders associated with aortic root aneurysms. Postgraduate Medical Journal, 92(1084), 112-117. https://doi.org/10.1136/postgradmedj-2013-305132rep

  • Korteland, N., Top, D., Borsboom, G., Hesselink, J., Bogers, A., & Takkenberg, H. (2016). Quality of life and prosthetic aortic valve selection in non-elderly adult patients. Interactive CardioVascular and Thoriac Surgery, 22(6), 723-728. https://doi.org/10.1093/icvts/ivw021

  • Mookhoek, A., Korteland, N., Arabkhani, B., Di Centa, I., Lansac, E., Bekkers, J., Bogers, A., & Takkenberg, H. (2016). Bentall Procedure: A Systematic Review and Meta-Analysis. Annals of Thoracic Surgery, 101(5), 1684-1690. https://doi.org/10.1016/j.athoracsur.2015.10.090

  • Huygens, S., Molken, M., Bekkers, J., Bogers, A., Bouten, CVC., Chamuleau, SAJ., Jaegere, P., Kappetein, A.-P., Kluin, J., Mieghem, N., Versteegh, MIM., Witsenburg, M., & Takkenberg, H. (2016). Conceptual model for early health technology assessment of current and novel heart valve interventions. Open Heart, 3, e000500. https://doi.org/10.1136/openhrt-2016-000500

  • Mokhles, M., Siregar, S., Versteegh, MIM., Noyez, L., van de Putte, B., Vonk, ABA., Hesselink, J., Bogers, A., & Takkenberg, H. (2016). Male-female differences and survival in patients undergoing isolated mitral valve surgery: a nationwide cohort study in the Netherlands. European Journal of Cardio-thoracic Surgery, 50(3), 482-487. https://doi.org/10.1093/ejcts/ezw151

  • Sievers, HH., Stierle, U., Charitos, EI., Takkenberg, H., Horer, J., Lange, R., Franke, U., Albert, M., Gorski, A., Leyh, R. G., Riso, A., Sachweh, J., Moritz, A., Hetzer, R., & Hemmer, W. (2016). A multicentre evaluation of the autograft procedure for young patients undergoing aortic valve replacement: update on the German Ross Registry. European Journal of Cardio-thoracic Surgery, 49(1), 212-218. https://doi.org/10.1093/ejcts/ezv001

  • Zacek, P., Holubec, T., Vobornik, M., Dominik, J., Takkenberg, H., Harrer, J., & Vojacek, J. (2016). Quality of life after aortic valve repair is similar to Ross patients and superior to mechanical valve replacement: a cross-sectional study. BMC Cardiovascular Disorders, 16, Article 63. https://doi.org/10.1186/s12872-016-0236-0

  • Arabkhani, B., Bekkers, J., Andrinopoulou, E., Hesselink, J., Takkenberg, H., & Bogers, A. (2016). Allografts in aortic position: Insights from a 27-year, single-center prospective study. Journal of Thoracic and Cardiovascular Surgery, 152(6), 1572-+. https://doi.org/10.1016/j.jtcvs.2016.08.013

  • Mookhoek, A., Krishnan, K., Chitsaz, S., Kuang, H. D., Ge, L., Schoof, P., Bogers, A., Takkenberg, H., & Tseng, EE. (2016). Biomechanics of Failed Pulmonary Autografts Compared With Normal Pulmonary Roots. Annals of Thoracic Surgery, 102(6), 1996-2002. https://doi.org/10.1016/j.athoracsur.2016.05.010

  • Huygens, S., Mokhles, M., Hanif, M., Bekkers, J., Bogers, A., Molken, M., & Takkenberg, H. (2016). Contemporary outcomes after surgical aortic valve replacement with bioprostheses and allografts: a systematic review and meta-analysis(aEuro). European Journal of Cardio-thoracic Surgery, 50(4), 605-616. https://doi.org/10.1093/ejcts/ezw101

  • Mookhoek, A., Takkenberg, H., & Bogers, A. (2016). Coronary Artery Pseudoaneurysm After Bentall Procedure Reply. Annals of Thoracic Surgery, 102(4), 1409-1410.

  • Skillington, PD., Mokhles, M., Takkenberg, H., Larobina, M., O'Keefe, M., Wynne, R., & Tatoulis, J. (2015). The Ross procedure using autologous support of the pulmonary autograft: Techniques and late results. Journal of Thoracic and Cardiovascular Surgery, 149(2), S46-S52. https://doi.org/10.1016/j.jtcvs.2014.08.068

  • Etnel, J., Takkenberg, H., Spaans, LG., Bogers, A., & Helbing, WA. (2015). Paediatric subvalvular aortic stenosis: a systematic review and meta analysis of natural history and surgical outcome. European Journal of Cardio-thoracic Surgery, 48, 212-220.

  • Mokhles, S., Nuyttens, JJME., Maat, Birim, O., Aerts, J., Bogers, A., & Takkenberg, H. (2015). Survival and Treatment of Non-small Cell Lung Cancer Stage I-II Treated Surgically or with Stereotactic Body Radiotherapy: Patient and Tumor-Specific Factors Affect the Prognosis. Annals of Surgical Oncology, 22(1), 316-323. https://doi.org/10.1245/s10434-014-3860-x

  • Mokhles, S., Verstegen, N., Maat, Birim, O., Bogers, A., Mokhles, M., Lagerwaard, FJ., Senan, S., & Takkenberg, H. (2015). Comparison of clinical outcome of stage I non-small cell lung cancer treated surgically or with stereotactic radiotherapy: Results from propensity score analysis. Lung Cancer, 87(3), 283-289. https://doi.org/10.1016/j.lungcan.2015.01.005

  • Charitos, EI., & Takkenberg, H. (2015). Repair or replace the aortic valve? more questions, no answers. Journal of Thoracic and Cardiovascular Surgery, 149(4), 1221-1222. https://doi.org/10.1016/j.jtcvs.2014.12.061

  • Schwarz, H., Kissler, J., de Jong, PL., Woestijne, P., Takkenberg, H., & Bogers, A. (2015). Clinical outcome and blood transfusion after infant cardiac surgery with a routine use of conventional ultrafiltration. Perfusion-Uk, 30(4), 323-331. https://doi.org/10.1177/0267659114546946

  • Sergeant, P., Takkenberg, H., & Noyez, L. (2015). The sequelae of misinterpretating surgical outcome data. Interactive CardioVascular and Thoriac Surgery, 20(6), 691-693. https://doi.org/10.1093/icvts/ivv060

  • Boks, R., Pelt, C., Takkenberg, H., & Bogers, A. (2015). Minimizing the perfusion system by integration of the components. Does it affect the hematocrit drop and transfused red blood cells? A retrospective audit. Perfusion-Uk, 30(2), 127-131. https://doi.org/10.1177/0267659114536456

  • Andrinopoulou, E., Rizopoulos, D., Geleijnse, M., Lesaffre, E., Bogers, A., & Takkenberg, H. (2015). Dynamic prediction of outcome for patients with severe aortic stenosis: application of joint models for longitudinal and time-to-event data. BMC Cardiovascular Disorders, 15, Article 28. https://doi.org/10.1186/s12872-015-0035-z

  • Smetsers, SE., Takkenberg, H., & Bierings, MB. (2015). Zorg voor patiënten met een zeldzame ziekten. Nederlands Tijdschrift voor Geneeskunde, 158, Article A7960.

  • Maat, Cornelissen, R., Bogers, A., & Takkenberg, H. (2015). Is the patient with mesothelioma without hope? Future Oncology, 11(24), 11-14. https://doi.org/10.2217/fon.15.184

  • Arabkhani, B., Mookhoek, A., Di Centa, I., Lansac, E., Bekkers, J., van Wijngaarden, RD., Bogers, A., & Takkenberg, H. (2015). Reported Outcome After Valve-Sparing Aortic Root Replacement for Aortic Root Aneurysm: A Systematic Review and Meta-Analysis. Annals of Thoracic Surgery, 100(3), 1126-1131. https://doi.org/10.1016/j.athoracsur.2015.05.093

  • Mokhles, S., Takkenberg, H., & Bogers, A. (2015). Surgery Versus Radiation Therapy in Stage I Lung Cancer. Annals of Thoracic Surgery, 100(5), 1968-1968.

  • Mookhoek, A., Charitos, EI., Hazekamp, MG., Bogers, A., Horer, J., Lange, R., Hetzer, R., Sachweh, JS., Riso, A., Stierle, U., Takkenberg, H., & Schoof, P. (2015). Ross Procedure in Neonates and Infants: A European Multicenter Experience. Annals of Thoracic Surgery, 100(6), 2278-2285. https://doi.org/10.1016/j.athoracsur.2015.08.008

  • Mookhoek, A., de Kerchove, L., El Khoury, G., Weimar, T., Luciani, GB., Mazzucco, A., Bogers, A., Aicher, D., Schafers, HJ., Charitos, EI., Stierle, U., & Takkenberg, H. (2015). European multicenter experience with valve-sparing reoperations after the Ross procedure. Journal of Thoracic and Cardiovascular Surgery, 150(5), 1132-1137. https://doi.org/10.1016/j.jtcvs.2015.08.043

  • Wal, T., Boks, R., Wijers-Hille, MJ., Hofland, H., Takkenberg, H., & Bogers, A. (2015). The effect of pre-operative blood withdrawal, with or without sequestration, on allogeneic blood product requirements. Perfusion-Uk, 30(8), 643-649. https://doi.org/10.1177/0267659115573097

  • Hartman, E., Groenendijk, I., Heuvelman, HM., Hesselink, J., Takkenberg, H., & Witsenburg, M. (2015). The effectiveness of stenting of coarctation of the aorta: a systematic review. EuroIntervention, 11(6), 660-668.

  • Louie, AV., Haasbeek, CJA., Mokhles, S., Rodrigues, GB., Stephans, KL., Lagerwaard, FJ., Palma, DA., Videtic, GMM., Warner, A., Takkenberg, H., Reddy, CA., Maat, Woody, NM., Slotman, BJ., & Senan, S. (2015). Predicting Overall Survival After Stereotactic Ablative Radiation Therapy in Early-Stage Lung Cancer: Development and External Validation of the Amsterdam Prognostic Model. International Journal of Radiation Oncology Biology Physics, 93(1), 82-90. https://doi.org/10.1016/j.ijrobp.2015.05.003

  • Huygens, S., Molken, M., Bekkers, J., Bogers, A., Bouten, CVC., Chamuleau, SAJ., Jaegere, P., Kappetein, A.-P., Kluin, J., Mieghem, N., Versteegh, MIM., Witsenburg, M., & Takkenberg, H. (2015). Development Of A Conceptual Model For Early Health Technology Assessment Of Tissue-Engineered Heart Valves. Value in Health, 18(7), Article A394. https://doi.org/10.1016/j.jval.2015.09.884

  • Rizopoulos, D., & Takkenberg, H. (2014). Tools & techniques - statistics: dealing with time varying covariates in survival analysis - joint models versus Cox models. EuroIntervention, 10, 285-288. https://doi.org/10.4244/EIJV10I2A47

  • Rizopoulos, D., Hatfield, L. A., Carlin, B. P., & Takkenberg, J. J. M. (2014). Combining Dynamic Predictions From Joint Models for Longitudinal and Time-to-Event Data Using Bayesian Model Averaging. Journal of the American Statistical Association, 109(508), 1385-1397. https://doi.org/10.1080/01621459.2014.931236

  • Wolvetang, T., Hofland, J., & Takkenberg, H. (2014). Knowlegde on malignant hyperthermia: as rare as the disease? A nation wide survey. BMC Anesthesiology, 14, Article A18.

  • Yacoub, MH., El-Hamamsy, I., Sievers, HH., Carabello, BA., Bonow, RO., Stelzer, P., da Costa, FDA., Schafers, HJ., Skillington, P., Charitos, EI., Luciani, GB., & Takkenberg, H. (2014). Under-use of the Ross operation-a lost opportunity. Lancet (UK), 384(9943), 559-560.

  • Treasure, T., Takkenberg, H., & Pepper, J. (2014). Personalised external aortic root support. Heart, 100(13), 1065-1066. https://doi.org/10.1136/heartjnl-2014-306136

  • Treasure, T., Takkenberg, H., & Pepper, J. (2014). Surgical management of aortic root disease in Marfan syndrome and other congenital disorders associated with aortic root aneurysms. Heart, 100(20), 1571-1576. https://doi.org/10.1136/heartjnl-2013-305132

  • Mokhles, M., Rajeswaran, J., Bekkers, J., Borsboom, G., Hesselink, J., Steyerberg, E., Bogers, A., Takkenberg, H., & Blackstone, EH. (2014). Capturing echocardiographic allograft valve function over time after allograft aortic valve or root replacement. Journal of Thoracic and Cardiovascular Surgery, 148(5), 1921-+. https://doi.org/10.1016/j.jtcvs.2014.04.023

  • Sergeant, PT., Takkenberg, H., & Pepper, J. (2014). Scientia vincere tenebras! Science should help us see in the darkness. European Journal of Cardio-thoracic Surgery, 45(2), 211-215. https://doi.org/10.1093/ejcts/ezt484

  • Treasure, T., Takkenberg, H., Golesworthy, T., Rega, F., Petrou, M., Rosendahl, U., Mohiaddin, R., Rubens, M., Thornton, W., Lees, B., & Pepper, J. (2014). Personalised external aortic root support (PEARS) in Marfan syndrome: analysis of 1-9 year outcomes by intention-to-treat in a cohort of the first 30 consecutive patients to receive a novel tissue and valve-conserving procedure, compared with the published results of aortic root replacement. Heart, 100(12). https://doi.org/10.1136/heartjnl-2013-304913

  • Andrinopoulou, E., Rizopoulos, D., Takkenberg, H., & Lesaffre, E. (2014). Joint modeling of two longitudinal outcomes and competing risk data. Statistics in Medicine, 33(18), 3167-3178. https://doi.org/10.1002/sim.6158

  • Bekkers, J., Riele, R., Takkenberg, H., Bol Raap, J., Hofland, H., Hesselink, J., & Bogers, A. (2014). Thoracic aortic surgery: An overview of 40 years clinical practice. Journal of Thoracic and Cardiovascular Surgery, 147(1), 332-343. https://doi.org/10.1016/j.jtcvs.2012.11.036

  • Korteland, N., Kluin, J., Klautz, RJM., Hesselink, J., Versteegh, MIM., Bogers, A., & Takkenberg, H. (2014). Cardiologist and cardiac surgeon view on decision-making in prosthetic aortic valve selection: does profession matter? Netherlands Heart Journal, 22(7-8), 336-343. https://doi.org/10.1007/s12471-014-0564-6

  • Vahanian, A., Alfieri, O., Andreotti, F., Antunes, MJ., Baron-Esquivias, G., Baumgartner, H., Borger, MA., Carrel, TP., De Bonis, M., Evangelista, A., Falk, V., Lung, B., Lancelotti, P., Pierard, L., Price, S., Schafers, HJ., Schuler, G., Stepinska, J., Swedberg, K., ... Zembala, M. (2014). Guidelines on the management of valvular heart disease (version 2012) The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology ( ESC) and the European Association for Cardio-Thoracic Surgery ( EACTS). Giornale Italiano di Cardiologia, 14, 167-214.

  • Takkenberg, H., Kappetein, A.-P., & Steyerberg, E. (2013). The role of EuroSCORE II in 21st century cardiac surgery practice. European Journal of Cardio-thoracic Surgery, 43(1), 32-33. https://doi.org/10.1093/ejcts/ezs271

  • Bakker, R., Akin, S., Rizopoulos, D., Kik, C., Takkenberg, H., & Bogers, A. (2013). Results of clinical application of the modified maze procedure as concomitant surgery. Interactive CardioVascular and Thoriac Surgery, 16(2), 151-156. https://doi.org/10.1093/icvts/ivs440

  • Heuvelman, H., Arabkhani, B., Cornette, JMJ., Pieper, PG., Bogers, A., Takkenberg, H., & Hesselink, J. (2013). Pregnancy Outcomes in Women With Aortic Valve Substitutes. American Journal of Cardiology, 111(3), 382-387. https://doi.org/10.1016/j.amjcard.2012.09.035

  • Ruys, T., Bosch, A., Cuypers, J., Witsenburg, M., Helbing, WA., Bogers, A., Domburg, R., Mcghie, J., Geleijnse, M., Henrichs, J., Utens, L., Zwaan, H., Takkenberg, H., & Hesselink, J. (2013). Long-term Outcome and Quality of Life after Arterial Switch Operation: A Prospective Study with a Historical Comparison. Congenital Heart Disease, 8(3), 203-210. https://doi.org/10.1111/chd.12033

  • Linde, D., Takkenberg, H., Rizopoulos, D., Heuvelman, H., Budts, W., van Dijk, APJ., Witsenburg, M., Yap, S., Bogers, A., Silversides, CK., Oechslin, EN., & Hesselink, J. (2013). Natural history of discrete subaortic stenosis in adults: a multicentre study. European Heart Journal, 34(21), 1548-1556. https://doi.org/10.1093/eurheartj/ehs421

  • Linde, D., Hesselink, J., Rizopoulos, D., Heuvelman, H., Budts, W., van Dijk, APJ., Witsenburg, M., Yap, S., Oxenius, A., Silversides, CK., Oechslin, EN., Bogers, A., & Takkenberg, H. (2013). Surgical Outcome of Discrete Subaortic Stenosis in Adults A Multicenter Study. Circulation, 127(11), 1184-+. https://doi.org/10.1161/CIRCULATIONAHA.112.000883

  • Siregar, S., Groenwold, RHH., Versteegh, MIM., Takkenberg, H., Bots, ML., van der Graaf, Y., & van Herwerden, LA. (2013). Data Resource Profile: Adult cardiac surgery database of the Netherlands Association for Cardio-Thoracic Surgery. International Journal of Epidemiology, 42(1), 142-149. https://doi.org/10.1093/ije/dys241

  • Takkenberg, H. (2013). Dynamic trends in cardiac surgery require dynamic models. European Journal of Cardio-thoracic Surgery, 43(6), 1153-1153. https://doi.org/10.1093/ejcts/ezs650

  • Bekkers, J., Raap, GB., Takkenberg, H., & Bogers, A. (2013). Acute type A aortic dissection: long-term results and reoperations. European Journal of Cardio-thoracic Surgery, 43(2), 389-396. https://doi.org/10.1093/ejcts/ezs342

  • Vahanian, A., Alfieri, O., Andreotti, F., Antunes, MJ., Baron-Esquivias, G., Baumgartner, H., Borger, MA., Carrel, TP., De Bonis, M., Evangelista, A., Falk, V., Lung, B., Lancellotti, P., Pierard, L., Price, S., Schafers, HJ., Schuler, G., Stepinska, J., Swedberg, K., ... Zembala, M. (2013). Guidelines on the management of valvular heart disease (version 2012) The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Revista Espanola de Cardiologia, 66(2), 2451-2496. https://doi.org/10.1093/eurheartj/ehs109

  • Battes, L., Barendse, RJ., Steyerberg, E., Simoons, M., Deckers, J., Nieboer, D., Bertrand, M., Ferrari, R., Remme, WJ., Fox, K., Takkenberg, H., Boersma, E., & Kardys, I. (2013). Development and Validation of a Cardiovascular Risk Assessment Model in Patients With Established Coronary Artery Disease. American Journal of Cardiology, 112(1), 27-33. https://doi.org/10.1016/j.amjcard.2013.02.049

  • Battes, L., Kardys, I., Barendse, RJ., Steyerberg, E., Amiri, M., Eijkemans, R., Deckers, J., Postmus, D., Takkenberg, H., Redekop, K., & Boersma, E. (2013). Microsimulation for Clinical Decision-Making in Individual Patients With Established Coronary Artery Disease - A Concept. Circulation Journal, 77(3), 717-724. https://doi.org/10.1253/circj.CJ-11-1300

  • Cornette, JMJ., Ruys, T., Rossi, A., Rizopoulos, D., Takkenberg, H., Karamermer, Y., Opic, P., Bosch, A., Geleijnse, M., Duvekot, JJ., Steegers, EAP., & Hesselink, J. (2013). Hemodynamic adaptation to pregnancy in women with structural heart disease. International Journal of Cardiology, 168(2), 825-831. https://doi.org/10.1016/j.ijcard.2012.10.005

  • Mokhles, M., Charitos, EI., Stierle, U., Rajeswaran, J., Blackstone, EH., Bogers, A., Takkenberg, H., & Sievers, HH. (2013). The fate of pulmonary conduits after the Ross procedure: longitudinal analysis of the German-Dutch Ross registry experience. Heart, 99(24), 1857-1866. https://doi.org/10.1136/heartjnl-2013-304425

  • Skillington, PD., Mokhles, M., Takkenberg, H., O'Keefe, M., Grigg, L., Wilson, W., Larobina, M., & Tatoulis, J. (2013). Twenty-Year Analysis of Autologous Support of the Pulmonary Autograft in the Ross Procedure. Annals of Thoracic Surgery, 96(3), 823-829. https://doi.org/10.1016/j.athoracsur.2013.04.019

  • Linde, D., Andrinopoulou, E., Oechslin, EN., Budts, W., van Dijk, APJ., Pieper, PG., Wajon, EMCJ., Post, MC., Witsenburg, M., Silversides, CK., Oxenius, A., Bogers, A., Takkenberg, H., & Hesselink, J. (2013). Congenital valvular aortic stenosis in young adults: Predictors for rate of progression of stenosis and aortic dilatation. International Journal of Cardiology, 168(2), 863-870. https://doi.org/10.1016/j.ijcard.2012.10.027

  • Geldorp, M., Heuvelman, H., Kappetein, A.-P., Busschbach, J., Cohen, DJ., Takkenberg, H., & Bogers, A. (2013). Quality of life among patients with severe aortic stenosis. Netherlands Heart Journal, 21(1), 21-27. https://doi.org/10.1007/s12471-012-0364-9

  • Geldorp, M., Heuvelman, H., Kappetein, A.-P., Busschbach, J., Takkenberg, H., & Bogers, A. (2013). The effect of aortic valve replacement on quality of life in symptomatic patients with severe aortic stenosis. Netherlands Heart Journal, 21(1), 28-35. https://doi.org/10.1007/s12471-012-0362-y

  • Boks, R., Schwarz, H., Takkenberg, H., & Bogers, A. (2012). Washing of irradiated red blood cells in paediatric cardiopulmonary bypass: is it clinically useful? A retrospective audit. European Journal of Cardio-thoracic Surgery, 41(2), 283-286. https://doi.org/10.1016/j.ejcts.2011.06.031

  • Schwarz, H., Boks, R., Takkenberg, H., & Bogers, A. (2012). Is it time to draw such a conclusion concerning the use of washed donor blood during paediatric cardiopulmonary bypass? Reply. European Journal of Cardio-thoracic Surgery, 41(6), 1408-1409. https://doi.org/10.1093/ejcts/ezr248

  • Head, S., Mokhles, M., Osnabrugge, R., Pibarot, P., Mack, MJ., Takkenberg, H., Bogers, A., & Kappetein, A.-P. (2012). The impact of prosthesispatient mismatch on long-term survival after aortic valve replacement: a systematic review and meta-analysis of 34 observational studies comprising 27 186 patients with 133 141 patient-years. European Heart Journal, 33(12), 1518-1529. https://doi.org/10.1093/eurheartj/ehs003

  • Andrinopoulou, E., Rizopoulos, D., Jin, RY., Bogers, A., Lesaffre, E., & Takkenberg, H. (2012). An Introduction to Mixed Models and Joint Modeling: Analysis of Valve Function Over Time. Annals of Thoracic Surgery, 93(6), 1765-1772. https://doi.org/10.1016/j.athoracsur.2012.02.049

  • Heuvelman, H., Geldorp, M., Eijkemans, R., Rajamannan, NM., Bogers, A., Hesselink, J., & Takkenberg, H. (2012). Progression of Aortic Valve Stenosis in Adults: A Systematic Review. Journal of Heart Valve Disease, 21(4), 454-462.

  • Mokhles, M., Rizopoulos, D., Andrinopoulou, E., Bekkers, J., Hesselink, J., Lesaffre, E., Bogers, A., & Takkenberg, H. (2012). Autograft and pulmonary allograft performance in the second post-operative decade after the Ross procedure: insights from the Rotterdam Prospective Cohort Study. European Heart Journal, 33(17), 2213-2224. https://doi.org/10.1093/eurheartj/ehs173

  • Mieghem, N., Head, S., Jong, W., Domburg, R., Serruys, PWJC., Jaegere, P., Jordaens, L., Takkenberg, H., Bogers, A., & Kappetein, A.-P. (2012). Persistent Annual Permanent Pacemaker Implantation Rate After Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis. Annals of Thoracic Surgery, 94(4), 1143-1149. https://doi.org/10.1016/j.athoracsur.2012.04.038

  • Mokhles, M., & Takkenberg, H. (2012). Invited commentary. Annals of Thoracic Surgery, 93(1), 57-58. https://doi.org/10.1016/j.athoracsur.2011.08.072

  • Takkenberg, H. (2012). Invited commentary. Annals of Thoracic Surgery, 93(2), 502.

  • Charitos, EI., Takkenberg, H., Hanke, T., Gorski, A., Botha, C., Franke, U., Dodge-Khatami, A., Hoerer, J., Lange, R., Moritz, A., Ferrari-Kuehne, K., Hetzer, R., Huebler, M., Bogers, A., Stierle, U., Sievers, HH., & Hemmer, W. (2012). Reoperations on the pulmonary autograft and pulmonary homograft after the Ross procedure: An update on the German Dutch Ross Registry. Journal of Thoracic and Cardiovascular Surgery, 144(4), 813-823. https://doi.org/10.1016/j.jtcvs.2012.07.005

  • Heuvelman, H., Geldorp, M., Kappetein, A.-P., Geleijnse, M., Galema, T., Bogers, A., & Takkenberg, H. (2012). Clinical course of patients diagnosed with severe aortic stenosis in the Rotterdam area: insights from the AVARIJN study. Netherlands Heart Journal, 20(12), 487-493. https://doi.org/10.1007/s12471-012-0309-3

  • Vahanian, A., Alfieri, O., Andreotti, F., Antunes, MJ., Baron-Esquivias, G., Baumgartner, H., Borger, MA., Carrel, TP., De Bonis, M., Evangelista, A., Falk, V., Iung, B., Lancellotti, P., Pierard, L., Price, S., Schafers, HJ., Schuler, G., Stepinska, J., Karl, S., ... Zembala, M. (2012). Guidelines on the management of valvular heart disease (version 2012). European Journal of Cardio-thoracic Surgery, 42(4), S1-S44. https://doi.org/10.1093/ejcts/ezs455

  • Arabkhani, B., Heuvelman, H., Bogers, A., Mokhles, M., Hesselink, J., & Takkenberg, H. (2012). Does Pregnancy Influence the Durability of Human Aortic Valve Substitutes? Journal of the American College of Cardiology, 60(19), 1991-1992. https://doi.org/10.1016/j.jacc.2012.06.055

  • Mokhles, M., Ciampichetti, I., Head, S., Takkenberg, H., & Bogers, A. (2011). Survival of Surgically Treated Infective Endocarditis: A Comparison With the General Dutch Population. Annals of Thoracic Surgery, 91(5), 1407-1413. https://doi.org/10.1016/j.athoracsur.2011.02.007

  • Bekkers, J., Klieverik, L., Bol Raap, J., Takkenberg, H., & Bogers, A. (2011). Re-operations for aortic allograft root failure: experience from a 21-year single-center prospective follow-up study. European Journal of Cardio-thoracic Surgery, 40(1), 35-42. https://doi.org/10.1016/j.ejcts.2010.11.025

  • Benedetto, U., Melina, G., Takkenberg, H., Roscitano, A., Angeloni, E., & Sinatra, R. (2011). Surgical management of aortic root disease in Marfan syndrome: a systematic review and meta-analysis. Heart, 97(12), 955-958. https://doi.org/10.1136/hrt.2010.210286

  • Head, S., Bogers, A., Serruys, PWJC., Takkenberg, H., & Kappetein, A.-P. (2011). A crucial factor in shared decision making: the team approach. Lancet (UK), 377(9780), 1836-1836. https://doi.org/10.1016/S0140-6736(11)60775-7

  • Schwarz, H., Scohy, TV., de Jong, PL., Kissler, J., Takkenberg, H., & Bogers, A. (2011). Relevance of colloid oncotic pressure regulation during neonatal and infant cardiopulmonary bypass: a prospective randomized study. European Journal of Cardio-thoracic Surgery, 39(6), 886-891. https://doi.org/10.1016/j.ejcts.2010.09.040

  • Mokhles, M., Bogaerdt, A., Takkenberg, H., & Bogers, A. (2011). Right Ventricular Outflow Tract Reconstruction: The Impact of Allograft Characteristics. Annals of Thoracic Surgery, 91(6), 2025-2025. https://doi.org/10.1016/j.athoracsur.2011.01.083

  • Leon, MB., Piazza, N., Nikolsky, E., Blackstone, EH., Cutlip, DE., Kappetein, A.-P., Krucoff, MW., Mack, M., Mehran, R., Miller, C., Petersen, J., Popma, JJ., Morel, M.-A., Takkenberg, H., Vahanian, A., Es, G., Vranckx, P., Webb, JG., Windecker, S., & Serruys, PWJC. (2011). Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium. European Heart Journal, 32(2), 205-U144. https://doi.org/10.1093/eurheartj/ehq406

  • Mokhles, M., Kortke, H., Stierle, U., Wagner, O., Charitos, EI., Bogers, A., Gummert, J., Sievers, HH., & Takkenberg, H. (2011). Survival Comparison of the Ross Procedure and Mechanical Valve Replacement With Optimal Self-Management Anticoagulation Therapy Propensity-Matched Cohort Study. Circulation, 123(1), 31-U85. https://doi.org/10.1161/CIRCULATIONAHA.110.947341

  • Gameren, M., Putman, L., Takkenberg, H., & Bogers, A. (2011). Risk stratification for adult congenital heart surgery. European Journal of Cardio-thoracic Surgery, 39(4), 490-494. https://doi.org/10.1016/j.ejcts.2010.07.032

  • Scohy, TV., Schwarz, H., Egal, M., Takkenberg, H., & Bogers, A. (2011). Intraoperative glycemic control without insulin infusion during pediatric cardiac surgery for congenital heart disease. Paediatric Anaesthesia, 21(8), 872-879. https://doi.org/10.1111/j.1460-9592.2011.03571.x

  • Mokhles, M., Bogers, A., & Takkenberg, H. (2011). Letter by Mokhles et al Regarding Article, "Prosthetic Heart Valve". Circulation, 124(24), E897-E897. https://doi.org/10.1161/CIRCULATIONAHA.111.050534

  • Linde, D., Yap, S., van Dijk, APJ., Budts, W., Pieper, PG., van der Burgh, PH., Mulder, BJM., Witsenburg, M., Cuypers, J., Lindemans, J., Takkenberg, H., & Hesselink, J. (2011). Effects of Rosuvastatin on Progression of Stenosis in Adult Patients With Congenital Aortic Stenosis (PROCAS Trial). American Journal of Cardiology, 108(2), 265-271. https://doi.org/10.1016/j.amjcard.2011.03.032

  • Leon, MB., Piazza, N., Nikolsky, E., Blackstone, EH., Cutlip, DE., Kappetein, A.-P., Krucoff, MW., Mack, M., Mehran, R., Miller, C., Morel, M.-A., Petersen, J., Popma, JJ., Takkenberg, H., Vahanian, A., Es, G., Vranckx, P., Webb, JG., Windecker, S., & Serruys, PWJC. (2011). Standardized Endpoint Definitions for Transcatheter Aortic Valve Implantation Clinical Trials A Consensus Report From the Valve Academic Research Consortium. Journal of the American College of Cardiology, 57(3), 253-269. https://doi.org/10.1016/j.jacc.2010.12.005

  • Linde, D., Konings, L., Slager, M., Witsenburg, M., Helbing, WA., Takkenberg, H., & Hesselink, J. (2011). Birth prevalence of congenital heart disease worldwide. Journal of the American College of Cardiology, 58(21), 2241-2247. https://doi.org/10.1016/j.jacc.2011.08.025

  • Bramer, S., Mokhles, M., Takkenberg, H., & Bogers, A. (2011). Long-term outcome of right ventricular outflow tract reconstruction with bicuspidalized homografts. European Journal of Cardio-thoracic Surgery, 40(6), 1392-1395. https://doi.org/10.1016/j.ejcts.2011.02.066

  • Mokhles, M., Bogers, A., & Takkenberg, H. (2011). No Ross Operation for Patients With Aortic Regurgitation? Annals of Thoracic Surgery, 92(3). https://doi.org/10.1016/j.athoracsur.2011.03.081

  • Woestijne, P., Mokhles, M., de Jong, PL., Witsenburg, M., Takkenberg, H., & Bogers, A. (2011). Right Ventricular Outflow Tract Reconstruction With an Allograft Conduit in Patients After Tetralogy of Fallot Correction: Long-Term Follow-Up. Annals of Thoracic Surgery, 92(1), 161-166. https://doi.org/10.1016/j.athoracsur.2011.02.036

  • Brown, JW., Elkins, RC., Clarke, DR., Tweddell, JS., Huddleston, CB., Doty, JR., Fehrenbacher, JW., & Takkenberg, H. (2010). Performance of the CryoValve* SG human decellularized pulmonary valve in 342 patients relative to the conventional CryoValve at a mean follow-up of four years. Journal of Thoracic and Cardiovascular Surgery, 139(2), 339-348. https://doi.org/10.1016/j.jtcvs.2009.04.065

  • El-Hamamsy, I., Eryigit, Z., Stevens, LM., Sarang, Z., George, R., Clark, L., Melina, G., Takkenberg, H., & Yacoub, MH. (2010). Long-term outcomes after autograft versus homograft aortic root replacement in adults with aortic valve disease: a randomised controlled trial. Lancet (UK), 376(9740), 524-531. https://doi.org/10.1016/S0140-6736(10)60828-8

  • Schwarz, H., Takkenberg, H., & Bogers, A. (2010). Specific requirements for bloodless cardiopulmonary bypass in neonates and infants; a review. Perfusion-Uk, 25(4), 237-243. https://doi.org/10.1177/0267659110375862

  • Mookhoek, A., de Heer, E., Bogers, A., Takkenberg, H., & Schoof, PH. (2010). Pulmonary autograft valve explants show typical degeneration. Journal of Thoracic and Cardiovascular Surgery, 139(6), 1416-1419. https://doi.org/10.1016/j.jtcvs.2010.01.020

  • El-Hamamsy, I., Clark, L., Stevens, LM., Sarang, Z., Melina, G., Takkenberg, H., & Yacoub, MH. (2010). Late Outcomes Following Freestyle Versus Homograft Aortic Root Replacement Results From a Prospective Randomized Trial. Journal of the American College of Cardiology, 55(4), 368-376. https://doi.org/10.1016/j.jacc.2009.09.030

  • Geldorp, M., Takkenberg, H., Bogers, A., & Kappetein, A.-P. (2010). New trends and Developments in patient with Severe Aortic stenosis-Toward Optimal Treatment. European Cardiology, 5, 81-84.

  • Horer, J., Stierle, U., Hanke, T., Takkenberg, H., Bogers, A., Hemmer, W., Rein, JG., Hubler, M., Hetzer, R., Sievers, HH., & Lange, R. (2010). Die Ross-Operation bei Kindern, ergebnisse aus dem Europaischen Ross-Register. Zeitschrift für herz-, Thorax- und Gefässchirurgie, 2, 115-121.

  • Sievers, HH., Stierle, U., Charitos, EI., Hanke, T., Misfeld, M., Bechtel, JFM., Gorski, A., Franke, UFW., Graf, B., Robinson, DR., Bogers, A., Dodge-Khatami, A., Boehm, JO., Rein, JG., Botha, CA., Lange, R., Hoerer, J., Moritz, A., Wahlers, T., ... Hemmer, W. (2010). Major Adverse Cardiac and Cerebrovascular Events After the Ross Procedure A Report From the German-Dutch Ross Registry. Circulation, 122(11), S216-S223. https://doi.org/10.1161/CIRCULATIONAHA.109.925800

  • Bekkers, J., Klieverik, L., Bol Raap, J., Takkenberg, H., & Bogers, A. (2010). Aortic root reoperations after pulmonary autograft implantation. Journal of Thoracic and Cardiovascular Surgery, S58-S63. https://doi.org/10.1016/j.jtcvs.2010.07.065

  • Takkenberg, H. (2010). Biological valves: is durability really the bottle neck? Heart, 96(21), 1691-1692. https://doi.org/10.1136/hrt.2010.207050

  • Geldorp, M., & Takkenberg, H. (2010). Prescribing statins in aortic stenosis: little to lose, much to gain Reply. European Journal of Cardio-thoracic Surgery, 37(2), 498-498.

  • Horer, J., Hanke, T., Stierle, U., Takkenberg, H., Bogers, A., Hemmer, W., Rein, JG., Hetzer, R., Hubler, M., Robinson, DR., Sievers, HH., & Lange, R. (2009). Neoaortic Root Diameters and Aortic Regurgitation in Children After the Ross Operation. Annals of Thoracic Surgery, 88(2), 594-600. https://doi.org/10.1016/j.athoracsur.2009.04.077

  • Takkenberg, H., Klieverik, L., Schoof, P., van Suylen, RJ., van Herwerden, LA., Zondervan, P., Hesselink, J., Eijkemans, R., Yacoub, MH., & Bogers, A. (2009). The Ross Procedure A Systematic Review and Meta-Analysis. Circulation, 119(2), 222-228. https://doi.org/10.1161/CIRCULATIONAHA.107.726349

  • Schwarz, H., Takkenberg, H., & Bogers, A. (2009). Risk factors for low colloid osmotic pressure during infant cardiopulmonary bypass with a colloidal prime. Interactive CardioVascular and Thoriac Surgery, 8, 512-516. https://doi.org/10.1510/icvts.2008.198283

  • Hartman, JM., Meijboom, B., Galema, T., Takkenberg, H., Schets, A., Feijter, P., & Bogers, A. (2009). Anatomical and functional assessment of single left internal mammary artery versus arteria T-grafts 12 years after surgery. Interactive CardioVascular and Thoriac Surgery, 9, 416-420. https://doi.org/10.1510/icvts.2008.199828

  • Takkenberg, H., & Hesselink, J. (2009). Rheumatic Heart Disease: The Quest for Optimal Screening. Journal of Heart Valve Disease, 18(3), 336-336.

  • Athanassopoulos, P., Balk, A., Vaessen, LMB., Caliskan, K., Takkenberg, H., Weimar, W., & Bogers, A. (2009). Blood dendritic cell levels and phenotypic characteristics in relation to etiology of end-stage heart failure: Implications for dilated cardiomyopathy. International Journal of Cardiology, 131(2), 246-256. https://doi.org/10.1016/j.ijcard.2007.10.031

  • Gameren, M., Piazza, N., Bogers, A., Takkenberg, H., & Kappetein, A.-P. (2009). How to assess risks of valve surgery: quality, implementation and future of risk models. Heart, 95(23), 1958-1963. https://doi.org/10.1136/hrt.2007.136259

  • Putman, L., Gameren, M., Meijboom, FJ., Jong, PL., Hesselink, J., Witsenburg, M., Takkenberg, H., & Bogers, A. (2009). Seventeen years of adult congenital heart surgery: a single centre experience. European Journal of Cardio-thoracic Surgery, 36(1), 96-104. https://doi.org/10.1016/j.ejcts.2009.01.046

  • Horer, J., Hanke, T., Stierle, U., Takkenberg, H., Bogers, A., Hemmer, W., Rein, JG., Hetzer, R., Hubler, M., Robinson, DR., Sievers, HH., & Lange, R. (2009). Homograft Performance in Children After the Ross Operation. Annals of Thoracic Surgery, 88(2), 609-615. https://doi.org/10.1016/j.athoracsur.2009.04.100

  • Geldorp, M., Gameren, M., Kappetein, A.-P., Arabin, B., Laat, L., Takkenberg, H., & Bogers, A. (2009). Therapeutic decisions for patients with symptomatic severe aortic stenosis: room for improvement? European Journal of Cardio-thoracic Surgery, 35(6), 953-957. https://doi.org/10.1016/j.ejcts.2009.01.043

  • Geldorp, M., Jamieson, WRE., Kappetein, A.-P., Ye, J., Fradet, GJ., Eijkemans, R., Grunkemeier, GL., Bogers, A., & Takkenberg, H. (2009). Patient outcome after aortic valve replacement with a mechanical or biological prosthesis: Weighing lifetime anticoagulant-related event risk against reoperation risk. Journal of Thoracic and Cardiovascular Surgery, 137(4), 881-U111. https://doi.org/10.1016/j.jtcvs.2008.09.028

  • Charitos, EI., Hanke, T., Stierle, U., Robinson, DR., Bogers, A., Hemmer, W., Bechtel, M., Misfeld, M., Gorski, A., Boehm, JO., Rein, JG., Botha, CA., Lange, R., Hoerer, J., Moritz, A., Wahlers, T., Franke, UFW., Breuer, M., Ferrari-Kuehne, K., ... Sievers, HH. (2009). Autograft Reinforcement to Preserve Autograft Function After the Ross Procedure A Report From the German-Dutch Ross Registry. Circulation, 120(11), S146-S154. https://doi.org/10.1161/CIRCULATIONAHA.108.843391

  • Klieverik, L., Yacoub, MH., Edwards, S., Bekkers, J., Hesselink, J., Kappetein, A.-P., Takkenberg, H., & Bogers, A. (2009). Surgical Treatment of Active Native Aortic Valve Endocarditis With Allografts and Mechanical Prostheses. Annals of Thoracic Surgery, 88(6), 1814-1821. https://doi.org/10.1016/j.athoracsur.2009.08.019

  • Gameren, M., Klieverik, L., Struijs, A., Venema, A., Kappetein, A.-P., Bogers, A., & Takkenberg, H. (2009). Impact of the definition of renal dysfunction on EuroSCORE performance. Journal of Cardiovascular Surgery, 50(5), 703-709.

  • Piazza, N., Gameren, M., Juni, P., Wenaweser, P., Carrel, T., Onuma, Y., Gahl, B., Heilige, G., Otten, AM., Kappetein, A.-P., Takkenberg, H., Domburg, R., Jaegere, P., Serruys, PWJC., & Windecker, S. (2009). A comparison of patient characteristics and 30-day mortality outcomes after transcatheter aortic valve implantation and surgical aortic valve replacement for the treatment of aortic stenosis: a two-centre study. EuroIntervention, 5(5), 580-588. https://doi.org/10.4244/EIJV5I5A94

  • Akins, CW., Miller, DC., Turina, MI., Kouchoukos, NT., Blackstone, EH., Grunkemeier, GL., Takkenberg, H., David, TE., Butchart, EG., Adams, DH., Shahian, DM., Hagl, S., Mayer, JE., & Lytle, BW. (2008). Guidelines for reporting mortality and morbidity after cardiac valve interventions. Journal of Thoracic and Cardiovascular Surgery, 135(4), 732-738.

  • Klieverik, L., Bekkers, J., Hesselink, J., Eijkemans, R., Bol Raap, J., Bogers, A., & Takkenberg, H. (2008). Autograft or allograft aortic valve replacement in young adult patients with congenital aortic valve disease. European Heart Journal, 29(11), 1446-1453. https://doi.org/10.1093/eurheartj/ehm589

  • Gameren, M., Kappetein, A.-P., Steyerberg, E., Venema, A., Berenschot, EAJ., Hannan, EL., Bogers, A., & Takkenberg, H. (2008). Do we need separate risk stratification models for hospital mortality after heart valve surgery? Annals of Thoracic Surgery, 85(3), 921-931. https://doi.org/10.1016/j.athoracsur.2007.11.074

  • Akins, CW., Miller, DC., Turina, MI., Kouchoukos, NT., Blackstone, EH., Grunkemeier, GL., Takkenberg, H., David, TE., Butchart, EG., Adams, DH., Shahian, DM., Hagl, S., Mayer, JE., & Lytle, BW. (2008). Guidelines for reporting mortality and morbidity after cardiac valve interventions. European Journal of Cardio-thoracic Surgery, 33(4), 523-528.

  • Otten, AM., Domburg, R., Gameren, M., Kappetein, A.-P., Takkenberg, H., Bogers, A., Serruys, PWJC., & Jaegere, P. (2008). Population characteristics, treatment assignment and survival of patients with aortic stenosis referred for percutaneous valve replacement. EuroIntervention, 4(2), 250-255.

  • Schwarz, H., Scohy, TV., Jong, PL., Takkenberg, H., & Bogers, A. (2008). Intraoperative cell salvage in infants undergoing elective cardiac surgery: a prospective trial. European Journal of Cardio-thoracic Surgery, 34(2), 354-359. https://doi.org/10.1016/j.ejcts.2008.04.047

  • Klieverik, L., Bogers, A., & Takkenberg, H. (2008). Is the Ross procedure really a Trojan horse: reply. European Heart Journal, 29(17), 2181-2182. https://doi.org/10.1093/eurheartj/ehn289

  • Wu, YX., Takkenberg, H., & Grunkemeier, GL. (2008). Measuring follow-up completeness. Annals of Thoracic Surgery, 85(4), 1155-1157. https://doi.org/10.1016/j.athoracsur.2007.12.012

  • Kappetein, A.-P., Geldorp, M., Takkenberg, H., & Bogers, A. (2008). Optimum management of elderly patients with calcified aortic stenosis. Expert Review of Cardiovascular Therapy, 6(4), 491-501. https://doi.org/10.1586/14779072.6.4.491

  • Grunkemeier, GL., Takkenberg, H., Jamieson, WRE., & Miller, DC. (2008). Reporting "actual freedom" should not be banned. Journal of Thoracic and Cardiovascular Surgery, 135(2), 460-462. https://doi.org/10.1016/j.jtcvs.2006.03.069

  • Takkenberg, H., Rajamannan, NM., Rosenhek, R., Kumar, AS., Carapetis, JR., & Yacoub, MH. (2008). The need for a global perspective on heart valve disease epidemiology - The SHVD working group on epidemiology of heart valve disease founding statement. Journal of Heart Valve Disease, 17(1), 135-139.

  • Yap, S., Kouwenhoven, M., Takkenberg, H., Galema, T., Meijboom, FJ., Domburg, R., Simoons, M., & Hesselink, J. (2007). Congenital aortic stenosis in adults: rate of progression and predictors of clinical outcome. International Journal of Cardiology, 122(3), 224-231. https://doi.org/10.1016/j.ijcard.2006.11.092

  • Klieverik, L., Takkenberg, H., Elbers, BCJ., Oei, FBS., van Herwerden, LA., & Bogers, A. (2007). Dissection of a dilated autograft root. Journal of Thoracic and Cardiovascular Surgery, 133(3), 817-818. https://doi.org/10.1016/j.jtcvs.2006.11.006

  • Kappetein, A.-P., Puvimanasinghe, JPA., Takkenberg, H., Steyerberg, E., & Bogers, A. (2007). Predicted patient outcome after aortic valve replacement with Medtronic Stentless Freestyle bioprostheses. Journal of Heart Valve Disease, 16(4), 423-428.

  • Grunkemeier, GL., Jin, RY., Eijkemans, R., & Takkenberg, H. (2007). Actual and actuarial probabilities of competing risks: Apples and lemons. Annals of Thoracic Surgery, 83(5), 1586-1592. https://doi.org/10.1016/j.athoracsur.2006.11.044

  • Takkenberg, H., Klieverik, L., Bekkers, J., Kappetein, A.-P., Hesselink, J., Eijkemans, R., & Bogers, A. (2007). Allografts for aortic valve or root replacement: insights from an 18-year singte-center prospective follow-up study. European Journal of Cardio-thoracic Surgery, 31(5), 851-858. https://doi.org/10.1016/j.ejcts.2007.02.009

  • Geldorp, M., Jamieson, WRE., Kappetein, A.-P., Puvimanasinghe, JPA., Eijkemans, R., Grunkemeier, GL., Takkenberg, H., & Bogers, A. (2007). Usefulness of microsimulation to translate valve performance into patient outcome: Patient prognosis after aortic valve replacement with the Carpentier-Edwards supra-annular valve. Journal of Thoracic and Cardiovascular Surgery, 134(3), 702-U6. https://doi.org/10.1016/j.jtcvs.2007.03.051

  • Klieverik, L., Takkenberg, H., Bekkers, J., Hesselink, J., Witsenburg, M., & Bogers, A. (2007). The Ross operation: a Trojan horse? European Heart Journal, 28(16), 1993-2000. https://doi.org/10.1093/eurheartj/ehl550

  • Schwarz, H., Takkenberg, H., van Gerner-Weelink, GL., Wijers, MJ., Scohy, TV., Jong, PL., & Bogers, A. (2007). Effects of cardiopulmonary bypass cicuit reduction and residual volume salvage on allogeneic transfusion requirements in infants undergoing cardiac surgery. Interactive CardioVascular and Thoriac Surgery, 6, 335-339. https://doi.org/10.1510/icvts.2006.141226

  • Schoof, PH., Takkenberg, H., van Suylen, RJ., Zondervan, P., Hazekamp, MG., Dion, RAE., & Bogers, A. (2006). Degeneration of the pulmonary autograft: An explant study. Journal of Thoracic and Cardiovascular Surgery, 132(6), 1426-1432. https://doi.org/10.1016/j.jtcvs.2006.07.035

  • Gameren, M., Witsenburg, M., Takkenberg, H., Boshoff, D., Mertens, L., van Oort, A., de Wolf, D., Freund, M., Sreeram, N., Bökenkamp, R., Talsma, MD., & Gewillig, M. (2006). Early complications of stenting in patients with congenital heart disease: a multicentre study. European Heart Journal, 27, 2709-2715. https://doi.org/10.1093/eurheartj/ehl328

  • Dos Reis Miranda, D., Klompe, L., Cademartiri, F., Haitsma, JJ., Palumbo, A., Takkenberg, H., Lachmann, BF., Bogers, A., & Gommers, D. (2006). The effect of open lung ventilation on right ventricular and left ventricular function in lung-lavaged pigs. Critical Care, 10(3). https://doi.org/10.1186/cc4944

  • Puvimanasinghe, JPA., Takkenberg, H., Eijkemans, R., van Herwerden, LA., Jamieson, WRE., Grunkemeier, GL., Habbema, D., & Bogers, A. (2006). Comparison of Carpentier-Edwards pericardial and supraannular bioprostheses in aortic valve replacement. European Journal of Cardio-thoracic Surgery, 29(3), 374-379. https://doi.org/10.1016/j.ejcts.2005.11.037

  • Klieverik, L., Noorlander, MS., Takkenberg, H., Kappetein, A.-P., Bekkers, J., van Herwerden, LA., & Bogers, A. (2006). Outcome after aortic valve replacement in young adults: Is patient profile more important than prosthesis type? Journal of Heart Valve Disease, 15(4), 479-487.

  • Yacoub, MH., Klieverik, L., Melina, G., Edwards, SER., Sarathchandra, P., Bogers, A., Squarcia, U., Sani, G., van Herwerden, LA., & Takkenberg, H. (2006). An evaluation of the ross operation in adults. Journal of Heart Valve Disease, 15(4), 531-539.

  • Takkenberg, H., van Herwerden, LA., Galema, T., Bekkers, J., Linkers, V., Eijkemans, R., & Bogers, A. (2006). Serial echocardiographic assessment of neo-aortic regurgitation and root dimensions after the modified Ross procedure. Journal of Heart Valve Disease, 15(1), 100-106.

  • Grunkemeier, GL., Takkenberg, H., Jamieson, WRE., & Miller, DC. (2006). An 'actual' problem: Another issue of apples and oranges. Response. Journal of Heart Valve Disease, 15(2), 305-306.

  • Kappetein, A.-P., Takkenberg, H., Puvimanasinghe, JPA., Jamieson, WRE., Eijkemans, R., & Bogers, A. (2006). Does the type of biological valve affect patient outcome? Interactive CardioVascular and Thoriac Surgery, 5, 398-402. https://doi.org/10.1510/icvts.2005.122382

  • Puvimanasinghe, JPA., Takkenberg, H., Eijkemans, R., Steyerberg, E., van Herwerden, LA., Grunkemeier, GL., Habbema, D., & Bogers, A. (2005). Prognosis after aortic valve replacement with the Carpentier-Edwards pericardial valve: Use of microsimulation. Annals of Thoracic Surgery, 80(3), 825-831. https://doi.org/10.1016/j.athoracsur.2005.03.064

  • Athanassopoulos, P., Vaessen, LMB., Balk, A., Takkenberg, H., Maat, Weimar, W., & Bogers, A. (2005). Impaired circulating dendritic cell reconstitution identifies rejecting recipients after clinical heart transplantation independent of rejection therapy. European Journal of Cardio-thoracic Surgery, 27(5), 783-789. https://doi.org/10.1016/j.ejcts.2004.12.032

  • Birim, O., Kappetein, A.-P., Takkenberg, H., Klaveren, RJ., & Bogers, A. (2005). Survival after pathological stage IA nonsmall cell lung cancer: Tumor size matters. Annals of Thoracic Surgery, 79(4), 1137-1141. https://doi.org/10.1016/j.athoracsur.2004.09.051

  • Thiel, RJ., Koopman, SR., Takkenberg, H., ten Harkel, ADJ., & Bogers, A. (2005). Metabolic alkalosis after pediatric cardiac surgery. European Journal of Cardio-thoracic Surgery, 28(2), 229-233. https://doi.org/10.1016/j.ejcts.2005.04.013

  • Takkenberg, H., Kappetein, A.-P., van Herwerden, LA., Witsenburg, M., Gevers, L., & Bogers, A. (2005). Pediatric autograft aortic root replacement: A prospective follow-up study. Annals of Thoracic Surgery, 80(5), 1628-1633. https://doi.org/10.1016/j.athoracsur.2005.04.057

  • Domburg, R., Lemos, PA., Takkenberg, H., Liu, TKK., van Herwerden, LA., Arampatzis, CH., Smits, PC., Daemen, J., Venema, A., Serruys, PWJC., & Bogers, A. (2005). The impact of the introduction of drug-eluting stents on the clinical practice of surgical and percutaneous treatment of coronary artery disease. European Heart Journal, 26(7), 675-681. https://doi.org/10.1093/eurheartj/ehi088

  • Domburg, R., Takkenberg, H., Noordzij, LJ., Saia, F., van Herwerden, LA., Serruys, PWJC., & Bogers, A. (2005). Late outcome after stenting or coronary artery bypass surgery for the treatment of multivessel disease: A single-center controlled cohort study matched-propensity. Annals of Thoracic Surgery, 79(5), 1563-1569. https://doi.org/10.1016/j.athoracsur.2004.11.031

  • Yacoub, MH., & Takkenberg, H. (2005). Will heart valve tissue engineering change the world? Nature Clinical Practice Cardiovascular Medicine, 2, 60-61. https://doi.org/10.1038/ncpcardio0112

  • Yap, S., Takkenberg, H., Witsenburg, M., Meijboom, FJ., & Hesselink, J. (2005). Aortic stenosis at young adult age. Expert Review of Cardiovascular Therapy, 6, 1087-1098. https://doi.org/10.1586/14779072.3.6.1087

  • Bogers, A., Kappetein, A.-P., Hesselink, J., & Takkenberg, H. (2004). Is a bicuspid aortic valve risk a factor for adverse outcome after an autograft procedure? Annals of Thoracic Surgery, 77, 1998-2003. https://doi.org/10.1016/j.athoracsur.2003.12.036

  • Puvimanasinghe, JPA., Takkenberg, H., Edwards, MB., Eijkemans, R., Steyerberg, E., van Herwerden, LA., Taylor, KM., Grunkemeier, GL., Habbema, D., & Bogers, A. (2004). Comparison of outcomes after aortic valve replacement with a mechanical valve or a bioprosthesis using microsimulation. Heart, 90, 1172-1178. https://doi.org/10.1136/hrt.2003.013102

  • Takkenberg, H., & Bogers, A. (2004). Allografts for aortic valve and root replacement: veni vidi vici? Expert Review of Cardiovascular Therapy, 2(1), 97-105. https://doi.org/10.1586/14779072.2.1.97

  • Hokken, RB., Takkenberg, H., van Herwerden, LA., Roelandt, J., & Bogers, A. (2003). Excessive pulmonary autograft dilatation causes important aortic regurgitation. Heart, 89, 933-934.

  • Puvimanasinghe, JPA., Takkenberg, H., Eijkemans, R., Steyerberg, E., van Herwerden, LA., Grunkemeier, GL., Habbema, D., & Bogers, A. (2003). Choice of a mechanical valve or a bioprosthesis for AVR: does CABG matter? European Journal of Cardio-thoracic Surgery, 23, 688-695. https://doi.org/10.1016/S1010-7940(03)00085-X

  • Takkenberg, H., Puvimanasinghe, JPA., van Herwerden, LA., Eijkemans, R., Steyerberg, E., Habbema, D., & Bogers, A. (2003). Decision-making in aortic valve replacement: bileaflet mechanical valves versus stented bioprotheses. Netherlands Heart Journal, 11(1), 5-10.

  • Takkenberg, H., Eijkemans, R., van Herwerden, LA., Steyerberg, E., Lane, MM., Elkins, RC., Habbema, D., & Bogers, A. (2003). Prognosis after aortic root replacement with cryopreserved allografts in adults. Annals of Thoracic Surgery, 75, 1482-1489. https://doi.org/10.1016/S0003-4975(02)04722-7

  • Takkenberg, H., Puvimanasinghe, JPA., & Grunkemeier, GL. (2003). Simulation models to predict outcome after aortic valve replacement. Annals of Thoracic Surgery, 75, 1372-1376. https://doi.org/10.1016/S0003-4975(02)04996-2

  • Takkenberg, H., van Herwerden, LA., Eijkemans, R., Bekkers, J., & Bogers, A. (2002). Evolution of allograft aortic valve replacement over 13 years: result of 275 procedures. European Journal of Cardio-thoracic Surgery, 21, 683-691. https://doi.org/10.1016/S1010-7940(02)00025-8

  • Takkenberg, H., Dossche, KME., Hazekamp, MG., Nijveld, A., Jansen, EWL., Waterbolk, TW., & Bogers, A. (2002). Report of the Dutch experience with the Ross procedure in 343 patients. European Journal of Cardio-thoracic Surgery, 22, 70-77. https://doi.org/10.1016/S1010-7940(02)00202-6

  • Venema, A., Takkenberg, H., Putten, N., de Jong, PL., & Bogers, A. (2002). Pediatric European cardiac surgical registry in the Thoraxcentre. Thoraxcentre Journal, 14(3), 64-67.

  • Domburg, R., Takkenberg, H., Meeter, K., Valk, S., van Herwerden, LA., & Bogers, A. (2002). Coronaire bypasschirurgie in 1971/80 en in 1995/96: toegenomen leeftijd en comorbiditeit, gelijke overlevingskans en minder vroege heringrepen 1 en 5 jaar na de operatie. Nederlands Tijdschrift voor Geneeskunde, 146(46), 2192-2196.

  • Domburg, R., Takkenberg, H., van Herwerden, LA., Venema, A., & Bogers, A. (2002). Short-term and 5-year outcome after primary isolated coronary artery bypass graft surgery: results of risk stratification in a bilocation center. European Journal of Cardio-thoracic Surgery, 21, 733-740. https://doi.org/10.1016/S1010-7940(02)00052-0

  • Takkenberg, H. (2002). Prognosis after autograft and allograft aortic root replacement. Evidence-based estimates using meta-analysis and microsimulation. Thesis. Thoraxcentre Journal, 14(2), 46-47.

  • Takkenberg, H., Puvimanasinghe, JPA., van Herwerden, LA., Steyerberg, E., Eijkemans, R., Habbema, D., & Bogers, A. (2001). Prognosis after aortic valve replacement with St. Jude Medical bileaflet prosthesis: impact on outcome of varying thromboembolic and bleeding hazards. European Heart Journal. Supplement, 3(Q), 27-32. https://doi.org/10.1016/S1520-765X(01)90039-2

  • Takkenberg, H., Eijgermans, MJM., van Herwerden, LA., Steyerberg, E., Grunkemeier, GL., Habbema, D., & Bogers, A. (2001). Estimated event-free life expectancy after autograft aortic root replacement in adults. Annals of Thoracic Surgery, 71, 344-348. https://doi.org/10.1016/S0003-4975(01)02559-0

  • Puvimanasinghe, JPA., Steyerberg, E., Takkenberg, H., Eijkemans, R., van Herwerden, LA., Bogers, A., & Habbema, D. (2001). Prognosis after aortic valve replacement with a bioprosthesis. Predictions based on meta-analysis and microsimulation. Circulation, 103, 1535-1541. http://hdl.handle.net/1765/9617

  • Gerestein, CG., Takkenberg, H., Oei, FBS., Cromme-Dijkhuis, AH., Spitaels, SEC., van Herwerden, LA., Steyerberg, E., & Bogers, A. (2001). Right ventricular outflow tract reconstruction with an allograft conduit. Annals of Thoracic Surgery, 71, 911-918. https://doi.org/10.1016/S0003-4975(00)02440-1

  • Plantinga, RF., Mulder, I., Takkenberg, H., Bennink, GBWE., Meijboom, FJ., & Bogers, A. (2001). De operatieve behandeling van het hypoplastisch linker hartsyndroom: beperkt succes. Nederlands Tijdschrift voor Geneeskunde, 145(2), 85-90.

  • Willems, TP., Takkenberg, H., Steyerberg, E., Linkers, V., Roelandt, J., Bos, E., & van Herwerden, LA. (2001). Human tissue valves in aortic position. Determinants of reoperation and valve regurgitation. Circulation, 103, 1515-1521.

  • Bogers, A., Takkenberg, H., Kappetein, AP., de Jong, PL., Cromme-Dijkhuis, AH., & Witsenburg, M. (2001). Is there a place for pediatric valvotomy in the autograft era. European Journal of Cardio-thoracic Surgery, 20, 89-94. https://doi.org/10.1016/S1010-7940(01)00712-6

  • Boks, R., van Herwerden, LA., Takkenberg, H., Gu, J., van Oeveren, W., Wijers, MJ., & Bogers, A. (2001). Is the use of albumin in colloid prime solution of cardiopulmonary bypass circuit justified? Annals of Thoracic Surgery, 72, 850-853. https://doi.org/10.1016/S0003-4975(01)02816-8

  • Takkenberg, H., Steyerberg, E., Puvimanasinghe, JPA., Eijkemans, R., van Herwerden, LA., Habbema, D., & Bogers, A. (2001). Evidence-based estimates of outcome after aortic valve replacement using a microsimulation model. Computers in Cardiology, 28, 141-144.

  • Bogers, A., & Takkenberg, H. (2000). Autograft procedure for aortic valve replacement in adolescents and adults. Thoraxcentre Journal, 12(3), 70-71.

  • Bogers, A., Akkersdijk, GP., de Jong, PL., Henrich, AH., Takkenberg, H., Domburg, R., & Witsenburg, M. (2000). Results of primary two-patch repair of complete atrioventricular septal defect. European Journal of Cardio-thoracic Surgery, 18, 473-479. https://doi.org/10.1016/S1010-7940(00)00536-4

  • Takkenberg, H., Denton, TA., Baak, R., Trento, A., Steyerberg, E., & van Herwerden, LA. (1999). Coronary artery bypass grafting after primary isolated aortic valve surgery. Journal of Thoracic and Cardiovascular Surgery, 118, 958-959. https://doi.org/10.1016/S0022-5223(99)70070-X

  • Takkenberg, H., Zondervan, P., & van Herwerden, LA. (1999). Progressive pulmonary autograft root dilatation and failure after Ross procedure. Annals of Thoracic Surgery, 67, 551-554. https://doi.org/10.1016/S0003-4975(98)01274-0

  • Sipkema, P., Takkenberg, H., Zeeuwe, PEM., & Westerhof, N. (1998). Left coronary pressure-flow relations of the beating and arrested rabbit heart at different ventricular volumes. Cardiovascular Research, 40, 88-95.

  • Aleksic, I., Freimark, D., Blanche, C., Czer, LSC., Takkenberg, H., Dalichau, H., Nessim, S., & Trento, A. (1997). Resting hemodynamics after total versus standard orthotopic heart transplantation in patients with high preoperative pulmonary vascular resistance. Thoracic and Cardiovascular Surgeon, 11, 1037-1044.

  • Aleksic, I., Freimark, D., Blanche, C., Czer, LSC., Dalichau, H., Valenza, M., Takkenberg, H., & Trento, A. (1997). The duration of administration of monoclonal antibody OKT 3 for induction immunosuppression after heart transplantation. Thoracic and Cardiovascular Surgeon, 45, 190-195.

  • Blanche, C., Nessim, S., Quartel, A., Takkenberg, H., Aleksic, I., Cohen, M., Czer, LSC., & Trento, A. (1997). Heart transplantation with bicaval and pulmonary venous anastomoses. A hemodynamic analysis of the first 117 patients. Journal of Cardiovascular Surgery, 38, 561-566.

  • Takkenberg, H., Wang, H.-M., Trento, A., Popov, A., Freimark, D., Eghbali, K., Hong Kai Wang, C., Blanche, C., & Czer, LSC. (1997). The effect of chronic alcohol use on the heart before and after transplantation in an experimental model in the rat. Journal of Heart and Lung Transplantation, 16, 939-945.

  • Aleksic, I., Czer, LSC., Freimar, D., Dalichau, H., Takkenberg, H., Blanche, C., Nessim, S., Nusser, P., & Trento, A. (1996). Heart transplantation in patients with diabetic end-organ damage before transplantation. Thoracic and Cardiovascular Surgeon, 44, 282-288.

Professional (2)
  • Takkenberg, H. (2005). Vrouwen gezocht voor topfuncties. Medisch Contact, 60, 452-454.

  • Takkenberg, H., & Bogers, A. (2003). Simulatiemodel helpt bij klepkeuze voor aortaklepvervanging. Cordiaal, 2, 21-24.

Academic (5)
  • Boks, R., Schwarz, H., Takkenberg, H., & Bogers, A. (2015). Washing of irradiated red blood cells in paediatric cardiopulmonary bypass: In M. J. Wijers Hille, & S. D. de Jong (Eds.), 15th European Congress On Extracorporeal Circulation Technology (pp. 214-226). FECECT.

  • Mokhles, M., & Takkenberg, H. (2014). Innovative statistical methods wich can be used to predit the performance of percardial valves and patient related outcomes over time. In The pericardial heart valve, the odyssey of a continuously evolving concept 1971-2014 (pp. 5). Society for cardiothoracic surgery.

  • Takkenberg, H., & Geldorp, M. (2010). Predicted patient outcome after bioprosthetic AVR and the Ross operation. In C. A. Yankah, Y. Weng, & R. Hetzer (Eds.), Aortic Root Surgery The biological Solution (pp. 530-538). Springer-Verlag.

  • Bechtel, JFM., Sievers, HH., Hanke, T., Stierle, U., Bogers, A., Hemmer, W., Bohm, JO., Rein, JG., Botha, CA., Lange, R., Horer, J., Moritz, A., Wahlers, T., Franke, UFW., Breuer, M., Ferrari-Kuhne, K., Hetzer, R., Hubler, M., Ziemer, G., ... Misfeld, M. (2010). The Ross operation: two decades of clinical experience. In CA. Yankah, Y. Weng, & R. Hetzer (Eds.), Aortic Root Surgery The biological Solution (pp. 74-88). Springer-Verlag.

  • Hazekamp, MG., Kurvers, MJM., Takkenberg, H., & Bogers, A. (1999). Late pulmonary valve insertion following Fallot repair. In M. M. Bartelings, & A. C. G. Wenink (Eds.), Congenital heart disease (pp. 1-1). Boerhaave commissie Postacademisch onderwijs in de geneeskun.

Professional (1)
  • Takkenberg, H. (2001). Resultaten met allografts en autografts voor vervanging van de aortawortel. In A. J. J. C. Bogers, & M. M. Bartelings (Eds.), The Rotterdam-Leiden seminars on cardiovascular anatomy and teratology 1999/2000/2001 (pp. 50-54). Erasmus Medical Center.

Academic (4)
  • Thijssen, C. G. E., Dekker, S., Bons, L. R., Geenen, L. W., Gökalp, A. L., Takkenberg, J. J. M., Mokhles, M. M., Bekkers, J. A., Boersma, E., Bouwens, E., van Kimmenade, R. R. J., & Roos-Hesselink, J. W. (2023). Reply to letter to the editor: “Novel biomarkers associated with thoracic aortic disease”. International Journal of Cardiology, 388, Article 131104. https://doi.org/10.1016/j.ijcard.2023.05.054

  • Notenboom, M. L., Bekkers, J. A., & Takkenberg, J. J. M. (2023). A left-shift in the diameter for prophylactic aneurysmectomy: The right decision for all? Journal of Thoracic and Cardiovascular Surgery, 166(2), e61-e62. https://doi.org/10.1016/j.jtcvs.2022.08.034

  • Takkenberg, J. J. M. (2022). Diversity Challenges and Opportunities for Randomized Controlled Trials in Cardiothoracic Surgery. Annals of Thoracic Surgery, 113(5), 1418-1419. https://doi.org/10.1016/j.athoracsur.2020.12.077

  • Veen, K. M., Notenboom, M. L., & Takkenberg, J. J. M. (2021). Letter by Veen et al Regarding Article, "Incidence and Clinical Significance of Worsening Tricuspid Regurgitation Following Surgical or Transcatheter Aortic Valve Replacement: Analysis From the PARTNER IIA Trial". Circulation. Cardiovascular interventions, 14(11), e011377. https://doi.org/10.1161/circinterventions.121.011377

Academic (1)
  • Bogers, A., & Takkenberg, H. (1999). Surgery for aortic stenosis beyond infancy, valvotomy or autograft. XXI congress of the European society of cardiology, Barcelona (Spain).

Internal (1)
  • Takkenberg, H. (2002). Prognosis after autograft and allograft aortic root replacement. Evidence-basded estimates using meta-analysis and microsimulation. [Doctoral Thesis, Erasmus University Rotterdam]. Erasmus Universiteit Rotterdam (EUR).

Popular (1)
  • Lindeboom, C., Coylewright, M., Etnel, J., Nieboer, A. P., Hartman, J., & Takkenberg, H. (2021). Shared Decision Making in the Heart Team: Current Team Attitudes and Review. Structural Heart: the journal of the Heart Team, 5(2), 163-167. https://doi.org/10.1080/24748706.2020.1859660

Academic (10)
  • Notenboom, M. L., Rhellab, R., Etnel, J. R. G., Huygens, S. A., Hjortnaes, J., Kluin, J., Takkenberg, J. J. M., & Veen, K. M. (2024). How microsimulation translates outcome estimates to patient lifetime event occurrence in the setting of heart valve disease. European Journal of Cardio-thoracic Surgery, 65(3), Article ezae087. https://doi.org/10.1093/ejcts/ezae087

  • Notenboom, M. L., Van Hoof, L., Schuermans, A., Takkenberg, J. J. M., Rega, F. R., & Taverne, Y. J. H. J. (2024). Aortic Valve Embryology, Mechanobiology, and Second Messenger Pathways: Implications for Clinical Practice. Journal of Cardiovascular Development and Disease, 11(2), Article 49. https://doi.org/10.3390/jcdd11020049

  • Yacoub, M. H., Notenboom, M. L., Melina, G., & Takkenberg, J. J. M. (2024). Surgical Heritage: You Had to Be There, Ross: The Comeback Kid. Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual, 27, 37-41. https://doi.org/10.1053/j.pcsu.2023.10.001

  • Meccanici, F., Notenboom, M. L., Meijssen, J., Smit, V., Van De Woestijne, P. C., Van Den Bosch, A. E., Helbing, W. A., Bogers, A. J. J. C., Takkenberg, J. J. M., & Roos-Hesselink, J. W. (2024). Long-term surgical outcomes of congenital supravalvular aortic stenosis: a systematic review, meta-analysis and microsimulation study. European Journal of Cardio-thoracic Surgery, 65(1), Article ezad360. https://doi.org/10.1093/ejcts/ezad360

  • Schuermans, A., Boerma, M., Sansoni, G. A., Van Den Eynde, J., Takkenberg, J. J. M., Helbing, W. A., Geva, T., Moons, P., Van De Bruaene, A., & Budts, W. (2023). Exercise in patients with repaired tetralogy of Fallot: A systematic review and meta-analysis. Heart, 109(13), 984-991. https://doi.org/10.1136/heartjnl-2022-321850

  • Mastrobuoni, S., Govers, P. J., Veen, K. M., Jahanyar, J., van Saane, S., Segreto, A., Zanella, L., de Kerchove, L., Takkenberg, J. J. M., & Arabkhani, B. (2023). Valve-sparing aortic root replacement using the reimplantation (David) technique: a systematic review and meta-analysis on survival and clinical outcome. Annals of Cardiothoracic Surgery, 12(3), 149-158. https://doi.org/10.21037/acs-2023-avs1-0038

  • Wang, X., Bakhuis, W., Veen, K. M., Bogers, A. J. J. C., Etnel, J. R. G., van Der Ven, C. C. E. M., Roos-Hesselink, J. W., Andrinopoulou, E. R., & Takkenberg, J. J. M. (2022). Outcomes after right ventricular outflow tract reconstruction with valve substitutes: A systematic review and meta-analysis. Frontiers in Cardiovascular Medicine, 9, Article 897946. https://doi.org/10.3389/fcvm.2022.897946

  • Meccanici, F., Gökalp, A. L., Thijssen, C. G. E., Mokhles, M. M., Bekkers, J. A., Van Kimmenade, R., Verhagen, H. J., Roos-Hesselink, J. W., & Takkenberg, J. J. M. (2022). Male-female differences in acute thoracic aortic dissection: A systematic review and meta-analysis. Interactive Cardiovascular and Thoracic Surgery, 34(4), 616-627. https://doi.org/10.1093/icvts/ivab270

  • Scheffers, L. E., Berg, L. E. M. V., Ismailova, G., Dulfer, K., Takkenberg, J. J. M., & Helbing, W. A. (2021). Physical exercise training in patients with a Fontan circulation: A systematic review. European Journal of Preventive Cardiology, 28(11), 1269-1278. https://doi.org/10.1177/2047487320942869

  • Kakar, E., Billar, R., Rosmalen, J., Klimek, M., Takkenberg, H., & Jeekel, J. (2021). Music intervention to relieve anxiety and pain in adults undergoing cardiac surgery: a systematic review and meta-analysis. Open Heart, 8(1), Article e001474. https://doi.org/10.1136/openhrt-2020-001474

Featured in the media